Objectives
- List the features of connective tissue that distinguish it from other basic tissues.
- Know the biochemical composition and sites of synthesis of the extracellular matrix components and how they associate with one another.
- Know the structure and function of the cell types found in connective tissue.
- Compare connective tissue types in terms of the types, amounts, and arrangement of their components.
- Relate the composition of each connective tissue type to its specific functions.
- Name body sites where each connective tissue type occurs, and relate the location of each type to its function.
- Recognize connective tissue cells and tissue types in micrographs, and predict their functions.
- Predict the functional consequences of a given structural defect in a connective tissue.
MAX-Yield™ Study Questions
3. Name the germ layer(s) from which connective tissue cells derive and the embryonic tissues containing undifferentiated connective tissue cells (I.E; II.E.1.a; III.D).
6. Name the structural glycoproteins of connective tissue ground substance and describe their functions (II.D.2).
7. Give some common causes of edema and describe their effects on the pressures acting on water in capillaries (IV.B).
Protein composition (II.A.1.a, B, and C)
Protein subunit arrangement (II.A.1.a, B, and C)
Distinctive amino acids (II.A.1.a, B, C.1.a and b)
Degree of glycosylation (II.B)
Arrangement and appearance (II.A, B, C.1.b and 2)
Diameter (II.A–C)
Physical properties and function (II.A.2 and 4, B and C.3)
Staining properties (II.A.3, B and C.2)
Location (II.A.5, B, and C.4)
Protein composition
Tendency to form fibers or fibrils
Tissue distribution
The cell responsible for their synthesis
10. Describe collagen synthesis and assembly, indicating the intracellular or extracellular location for each step (II.A.1.a and b; Fig. 5-1).
Collagenase (IV.E)
Elastase (II.C.1.b)
Signal peptidase (2.III.C.1.b)
Lysyl oxidase (II.A.1.b and C.1.b)
Procollagen peptidase (II.A.1.b)
Proline hydroxylase (II.A.1.a)
14. Compare fibroblasts and fibrocytes (II.E.1.b) in terms of shape, nuclear morphology, and activity (mitotic and synthetic).
16. Name the organelles that are abundant in macrophages and indicate their major function (II.E.2.b).
Shape and size
Staining properties
Granule contents
Cause of degranulation
Effects of degranulation
Role in allergic reactions
Shape
Staining properties
Nuclear morphology
Major cytoplasmic organelles
Major secretory product
Role in immunity
Blood cell precursor
20. Name three types of connective tissue proper. Compare them in terms of function and location (III.A.1, 2.a and b).
Abundance
Matrix composition
Fiber bundle thickness
Number of cells
Flexibility and resistance to stress
Collagen turnover rate (IV.E)
Location
22. Compare dense regular and irregular connective tissues in terms of collagen bundle arrangement and location (III.A.2.a and b).
23. Describe reticular connective tissue in terms of its appearance location, predominant cell type, and function (III.B).
24. Describe elastic connective tissue in terms of composition, primary cell type, and location (III.C).
25. Describe mucous connective tissue in terms of its primary matrix component and cell type, consistency, and location (III.D).
26. Discuss the active and passive roles of connective tissue in preventing pathogen invasion (IV.A.2.a, b).
28. Which connective tissue cells contribute to wound repair by removing and replacing damaged tissue (IV.A.3)?