Antibody Index



Antibody Index


Mohammad A. Vasef, MD
















































































































































































































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Jun 13, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Antibody Index
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    Antibodies Discussed


    Antibody Name/Symbol


    Antibody Description


    Clones/Alternative Names


    Chapters


    β-2-microglobulin


    component of MHC class I molecules


    B2-MICROGLB


    Lymphoplasmacytic Lymphoma; Splenic B-cell Marginal Zone Lymphoma


    κ light chain


    kappa light chain


    KAPPA



    λ light chain


    lambda light chain


    LAMBDA



    AE1


    detects a variety of low to intermediate molecular weight cytokeratins



    Hematopoiesis and Bone Marrow Histology


    AE1/AE3


    mixture of 2 anticytokeratin clones that detect a variety of both high and low molecular weight cytokeratins



    Metastatic Carcinoma and Sarcoma


    ALK


    anaplastic lymphoma kinase-1


    5A4, ALK1, ALKC


    Anaplastic Large Cell Lymphoma in Blood and Bone Marrow; Overview and Classification of Mature Leukemias, Immunosecretory Lymphomas; Overview and Classification of Mature T/NK-Cell Neoplasms; Overview of Lymphoid Neoplasms; Protocol for the Examination of Specimens from Patients with Non-Hodgkin Lymphoma/Lymphoid Neoplasms


    ALK1


    anaplastic lymphoma kinase-1


    5A4, ALK, ALKC


    Anaplastic Large Cell Lymphoma in Blood and Bone Marrow; Bone Marrow Examination and Techniques; Hodgkin Lymphoma in Bone Marrow, Classic and Lymphocyte Predominant Subtypes


    Annexin-A1


    mediator of anti-inflammatory response and upregulated in hairy cell leukemia


    ANXA1, LPC1, lipocortin


    Hairy Cell Leukemia; Pancytopenia


    Bcl-2


    B-cell CLL lymphoma 2; suppresses apoptosis in a variety of cell systems


    ONCL2, BCL2/100/D5, 124, 124.3


    Burkitt Leukemia/Lymphoma; Chronic Lymphocytic Leukemia/small Lymphocytic Lymphoma; Hairy Cell Leukemia; Other B-cell Non-Hodgkin Lymphomas Involving Blood and Bone Marrow; Plasma Cell Myeloma


    Bcl-6


    B-cell CLL lymphoma 6


    LN22, GI191E/A8, N-3, PG-B6P, P1F6, 3FR-1


    Hodgkin Lymphoma in Bone Marrow, Classic and Lymphocyte Predominant Subtypes; Lymphoid Aggregates in Bone Marrow; Other B-cell Non-Hodgkin Lymphomas Involving Blood and Bone Marrow; Overview and Classification of Mature Leukemias, Immunosecretory Lymphomas; Splenic B-cell Marginal Zone Lymphoma


    BRCA1


    breast and ovarian cancer susceptibility protein 1


    MS110


    Fanconi Anemia


    CD1a


    T-cell surface glycoprotein


    JPM30, CD1A, O10, NA1/34


    Langerhans Cell Histiocytosis in Bone Marrow; Lysosomal Storage Diseases with Predominantly Histiocytic Storage; Other T-cell Non-Hodgkin Lymphomas Involving Blood and Bone Marrow; T-cell Prolymphocytic Leukemia; T-lymphoblastic Leukemia/Lymphoma


    CD2


    T-cell surface antigen, LFA2


    271, MT910, AB75, LFA-2


    Acute Promyelocytic Leukemia with t(15;17) (q22;q21);PML-RARA and Variants; Acute Myeloid Leukemia with t(8;21)(q22;q22) RUNX1-RUNX1T1; Anaplastic Large Cell Lymphoma in Blood and Bone Marrow; B Lymphoblastic Leukemia; Chronic Myelomonocytic Leukemia; Mast Cell Leukemia; Overview and Classification of Mature T/NK-Cell Neoplasms; Overview of Myeloproliferative Neoplasms; Paroxysmal Nocturnal Hemoglobinuria; Post-Transplant Lymphoproliferative Disorders in Bone Marrow; Systemic Mastocytosis; T-cell Prolymphocytic Leukemia; T-lymphoblastic Leukemia/Lymphoma


    CD3




    Acquired Aplastic Anemia; Acute Undifferentiated Leukemia; Adult T-cell Leukemia; Aggressive NK-cell Leukemia; Anaplastic Large Cell Lymphoma in Blood and Bone Marrow; Bone Marrow Examination and Techniques; Chronic Lymphoproliferative Disorder of NK Cells; Hematopoiesis and Bone Marrow Histology; Hodgkin Lymphoma in Bone Marrow, Classic and Lymphocyte Predominant Subtypes; Human Immunodeficiency Virus; Infectious Mononucleosis Syndromes (Epstein-Barr Virus, Cytomegalovirus); Lymphoid Aggregates in Bone Marrow; Lymphopenia, Constitutional and Acquired; Mixed Phenotype Acute Leukemia; Mycosis Fungoides/Sézary Syndrome; Other T-cell Non-Hodglin Lymphomas Involving Blood and Bone Marrow; Overview and Classification of Hemophagocytic Disorders in Bone Marrow; Overview and Classification of Mature T/NK-Cell Neoplasms; Post-Transplant Lymphoproliferative Disorders in Bone Marrow; Systemic Mastocytosis; T-cell Large Granular Lymphocytic Leukemia; T-cell Prolymphocytic Leukemia; T-lymphoblastic Leukemia/Lymphoma


    CD4


    T-cell surface glycoprotein L3T4


    IF6, 1290, 4B12


    Acute Monoblastic and Monocytic Leukemia; Acute Myeloid Leukemia with Maturation; Acute Myeloid Leukemia with t(9;11)(p22;q23); MLLT3-MLL; Anaplastic Large Cell Lymphoma in Blood and Bone Marrow; Blastic Plasmacytoid Dendritic Cell Neoplasm; Bone Marrow Examination and Techniques; Burkitt Leukemia/Lymphoma; Fungal Infections, Blood and Bone Marrow Features; Human Immunodeficiency Virus; Infectious Mononucleosis Syndromes (Epstein-Barr Virus, Cytomegalovirus); Langerhans Cell Histiocytosis in Bone Marrow; Lymphopenia, Constitutional and Acquired; Mycosis Fungoides/Sézary Syndrome; Other T-cell Non-Hodgkin Lymphomas Involving Blood and Bone Marrow; Overview and Classification of Mature T/NK-Cell Neoplasms; Overview of Acute Myeloid Leukemia; Post-Transplant Lymphoproliferative Disorders in Bone Marrow; T-cell Large Granular Lymphocytic Leukemia; T-cell Prolymphocytic Leukemia; Tlymphoblastic Leukemia/Lymphoma


    CD5


    T-cell surface glycoprotein Leu 1, T1


    NCL-CD5, 4C7, 54/B4, 54/F6


    Anaplastic Large Cell Lymphoma in Blood and Bone Marrow; B-cell Prolymphocytic Leukemia; Bone Marrow Examination and Techniques; Chronic Lymphocytic Leukemia/small Lymphocytic Lymphoma; Chronic Lymphoproliferative Disorder of NK Cells; Hairy Cell Leukemia; Hematogones in Bone Marrow; Infectious Mononucleosis Syndromes (Epstein-Barr Virus, Cytomegalovirus); Lymphoid Aggregates in Bone Marrow; Mycosis Fungoides/Sézary Syndrome; Other B-cell Non-Hodgkin Lymphomas Involving Blood and Bone Marrow; Overview and Classification of Mature Leukemias, Immunosecretory Lymphomas; Overview and Classification of Mature T/NK-Cell Neoplasms; Overview and Classification of Myelodysplastic Syndromes; Overview of Lymphoid Neoplasms; Splenic B-cell Marginal Zone Lymphoma; T-cell Large Granular Lymphocytic Leukemia; T-cell Prolymphocytic Leukemia; T-lymphoblastic Leukemia/Lymphoma


    CD7


    T-cell antigen precursor Leu 9


    272, CD7-272


    Acute Monoblastic and Monocytic Leukemia; Acute Myelomonocytic Leukemia; Adult T-cell Leukemia; Acute Myeloid Leukemia with Maturation; Acute Myeloid Leukemia with Minimal Differentiation; Acute Myeloid Leukemia without Maturation; B Lymphoblastic Leukemia; Blastic Plasmacytoid Dendritic Cell Neoplasm; Mycosis Fungoides/Sézary Syndrome; Other T-cell Non-Hodgkin Lymphomas Involving Blood and Bone Marrow; Overview and Classification of Mature T/NK-Cell Neoplasms; Post-Transplant Lymphoproliferative Disorders in Bone Marrow; Refractory Anemia With Excess Blasts; T-cell Large Granular Lymphocytic Leukemia; T-cell Prolymphocytic Leukemia; Tlymphoblastic Leukemia/Lymphoma


    CD8


    T-cell coreceptor antigen, Leu 2, Tcytotoxic cells


    M7103, C8/144, C8/144B


    Anaplastic Large Cell Lymphoma in Blood and Bone Marrow; Bone Marrow Examination and Techniques; Chronic Lymphoproliferative Disorder of NK Cells; Infectious Mononucleosis Syndromes (Epstein-Barr Virus, Cytomegalovirus); Mycosis Fungoides/Sézary Syndrome; Other T-cell Non-Hodgkin Lymphomas Involving Blood and Bone Marrow; Overview and Classification of Hemophagocytic Disorders in Bone Marrow; Overview and Classification of Mature T/NK-Cell Neoplasms; Post-Transplant Lymphoproliferative Disorders in Bone Marrow; Protocol for the Examination of Specimens from Patients with Non-Hodgkin Lymphoma/Lymphoid Neoplasms; T-cell Large Granular Lymphocytic Leukemia; T-cell Prolymphocytic Leukemia; T-lymphoblastic Leukemia/Lymphoma; WAS-related Disorders


    CD10


    neutral endopeptidase


    CALLA, neprilysin, NEP


    Acute Undifferentiated Leukemia; B Lymphoblastic Leukemia; Burkitt Leukemia/Lymphoma; Chronic Lymphocytic Leukemia/small Lymphocytic Lymphoma; Chronic Myelogenous Leukemia, BCR-ABL1+; Hairy Cell Leukemia; Hematogones in Bone Marrow; Lymphoid Aggregates in Bone Marrow; Lymphoplasmacytic Lymphoma; Mixed Phenotype Acute Leukemia; Other B-cell Non-Hodgkin Lymphomas Involving Blood and Bone Marrow; Other T-cell Non-Hodgkin Lymphomas Involving Blood and Bone Marrow; Overview and Classification of Mature Leukemias, Immunosecretory Lymphomas; Overview of Lymphoid Neoplasms; T-lymphoblastic Leukemia/Lymphoma


    CD11c


    integrin alpha X chain protein


    LEU-M5


    Acute Monoblastic and Monocytic Leukemia; Acute Myelomonocytic Leukemia; Acute Myeloid Leukemia with Maturation; Chronic Lymphocytic Leukemia/small Lymphocytic Lymphoma; Hairy Cell Leukemia;


    CD12



    CDw12


    Blastic Plasmacytoid Dendritic Cell Neoplasm


    CD13


    plays role in growth of DC/macrophage progenitors and precursors



    Acute Megakaryoblastic Leukemia; Acute Monoblastic and Monocytic Leukemia; Acute Panmyelosis with Myelofibrosis; Acute Promyelocytic Leukemia with t(15;17) (q22;q21);PML-RARA and Variants; Acute Undifferentiated Leukemia; Acute Myeloid Leukemia with t(9;11)(p22;q23); MLLT3-MLL; B-Lymphoblastic Leukemia; Mast Cell Leukemia; Mixed Phenotype Acute Leukemia; Monocytosis; Overview and Classification of Myelodysplastic Syndromes; Refractory Anemia With Excess Blasts


    CD14


    coreceptor for lipopolysaccharide binding protein


    FMC32


    Acute Monoblastic and Monocytic Leukemia; Acute Myeloid Leukemia with inv(16)(p13.1;q22) or t(16;16)(p13.1;q22); CBFB-MYH11; Acute Myeloid Leukemia with t(9;11)(p22;q23); MLLT3-MLL; Blastic Plasmacytoid Dendritic Cell Neoplasm; Mast Cell Leukemia; Monocytosis; Paroxysmal Nocturnal Hemoglobinuria


    CD15


    reacts with Reed-Sternberg cells of Hodgkin disease and with granulocytes


    VIM-2,3C4, LEU-M1, TU9, VIMD5, MY1, CBD1, MMA, 3CD1, C3D1, Lewis x, SSEA-1


    Acute Monoblastic and Monocytic Leukemia; Acute Myelomonocytic Leukemia; Acute Promyelocytic Leukemia with t(15;17)(q22;q21);PML-RARA and Variants; Acute Myeloid Leukemia with Maturation; Anaplastic Large Cell Lymphoma in Blood and Bone Marrow; Hodgkin Lymphoma in Bone Marrow, Classic and Lymphocyte Predominant Subtypes; Mast Cell Leukemia; Other T-NHL Involving Blood and Bone Marrow; Overview and Classification of Myelodysplastic Syndromes; Post-Transplant Lymphoproliferative Disorders in Bone Marrow


    CD16


    Fc receptor of IgG



    Chronic Lymphoproliferative Disorder of NK Cells; Monocytosis; Other T-NHL Involving Blood and Bone Marrow; Overview and Classification of Mature T/NK-Cell Neoplasms; Overview and Classification of Myelodysplastic Syndromes; Paroxysmal Nocturnal Hemoglobinuria; T-cell Large Granular Lymphocytic Leukemia


    CD19


    B-cell antigen



    Acute Undifferentiated Leukemia; Acute Myeloid Leukemia with t(8;21)(q22;q22) RUNX1-RUNX1T1; B Lymphoblastic Leukemia; Chronic Lymphocytic Leukemia/small Lymphocytic Lymphoma; Chronic Myelogenous Leukemia, BCR-ABL-1+; Hematogones in Bone Marrow; Lymphoid Aggregates in Bone Marrow; Mixed Phenotype Acute Leukemia; Overview and Classification of Mature Leukemias, Immunosecretory Lymphomas; Plasma Cell Myeloma; Splenic B-cell Marginal Zone Lymphoma


    CD20


    membrane spanning 4 domains of Blymphocytes


    FB1, B1, L26, MS4A1


    Acquired Aplastic Anemia; B Lymphoblastic Leukemia; Blastic Plasmacytoid Dendritic Cell Neoplasm; Burkitt Leukemia/Lymphoma; Chronic Lymphocytic Leukemia/small Lymphocytic Lymphoma; Granulomas in Bone Marrow; Hairy Cell Leukemia; Hematogones in Bone Marrow; Hematopoiesis and Bone Marrow Histology; Hodgkin Lymphoma in Bone Marrow, Classic and Lymphocyte Predominant Subtypes; Human Immunodeficiency Virus; Infectious Mononucleosis Syndromes (Epstein-Barr Virus, Cytomegalovirus); Lymphoid Aggregates in Bone Marrow; Lymphoplasmacytic Lymphoma; Other B-cell Non-Hodgkin Lymphomas Involving Blood and Bone Marrow; Overview and Classification of Mature Leukemias, Immunosecretory Lymphomas; Overview of Lymphoid Neoplasms; Pancytopenia; Plasma Cell Myeloma; Splenic B-cell Leukemia; Hairy Cell Leukemia Variant; Splenic B-cell Marginal Zone Lymphoma; Systemic Mastocytosis


    CD21


    CR2, complement component receptor 2, Epstein-Barr virus receptor


    IF8


    Langerhans Cell Histiocytosis in Bone Marrow


    CD22


    B-cell receptor


    FPC1, LEU 14


    Bone Marrow Examination and Techniques; Chronic Lymphocytic Leukemia/small Lymphocytic Lymphoma; Hairy Cell Leukemia; Lymphoplasmacytic Lymphoma


    CD23


    Fc ε RII, low-affinity IgE receptor, IGEBF


    1B12, MHM6BU38


    Burkitt Leukemia/Lymphoma; Chronic Lymphocytic Leukemia/small Lymphocytic Lymphoma; Hairy Cell Leukemia; Lymphoplasmacytic Lymphoma; Other B-cell Non-Hodgkin Lymphomas Involving Blood and Bone Marrow; Overview of Lymphoid Neoplasms; Splenic B-cell Marginal Zone Lymphoma


    CD24


    sialic acid epitope of B lymphocytes


    BA-1


    Paroxysmal Nocturnal Hemoglobinuria


    CD25


    If-2 receptor alpha


    2A3, 4C9


    Acute Myeloid Leukemia with t(8;21)(q22;q22) RUNX1-RUNX1T1; B Lymphoblastic Leukemia; Basophilia; Chronic Lymphocytic Leukemia/small Lymphocytic Lymphoma; Hairy Cell Leukemia; Mast Cell Leukemia; Overview and Classification of Hemophagocytic Disorders in Bone Marrow; Overview and Classification of Mature Leukemias, Immunosecretory Lymphomas; Overview and Classification of Mature T/NK-Cell Neoplasms; Overview of Myeloproliferative Neoplasms; Splenic B-cell Leukemia; Hairy Cell Leukemia Variant; Systemic Mastocytosis; T-cell Large Granular Lymphocytic Leukemia; T-cell Prolymphocytic Leukemia


    CD27


    TNF receptor



    Lymphoplasmacytic Lymphoma


    CD30


    tumor necrosis factor SF8


    BER-H2, KI-1, TNFRSF8


    Anaplastic Large Cell Lymphoma in Blood and Bone Marrow; Hodgkin Lymphoma in Bone Marrow, Classic and Lymphocyte Predominant Subtypes; Lymphoid Aggregates in Bone Marrow; Mast Cell Leukemia; Overview and Classification of Mature T/NK-Cell Neoplasms; Overview of Lymphoid Neoplasms; Post-Transplant Lymphoproliferative Disorders in Bone Marrow


    CD31


    platelet endothelial cell adhesion molecule


    JC/70, JC/70A, PECAM-1


    Acute Megakaryoblastic Leukemia; Acute Myeloid Leukemia with Minimal Differentiation; Chronic Myelogenous Leukemia, BCR-ABL1+; MDS with Isolated del (5q); Myeloid Proliferations Related to Down Syndrome; Myeloproliferative Neoplasm, Unclassifiable; Overview and Classification of Myeloid Neoplasms; Overview of Megakaryocytic Disorders; Pregnancy-associated Hematologic Disorders


    CD33


    SIGLEC lectin 3


    PWS44


    Acute Megakaryoblastic Leukemia; Acute Monoblastic and Monocytic Leukemia; Acute Undifferentiated Leukemia; Acute Myeloid Leukemia with inv(16)(p13.1;q22) or t(16;16) (p13.1;q22); CBFB-MYH11; Acute Myeloid Leukemia with Maturation; Acute Myeloid Leukemia with Minimal Differentiation; Acute Myeloid Leukemia with t(8;21)(q22;q22) RUNX1-RUNX1T1; Acute Myeloid Leukemia with t(9;11)(p22;q23); MLLT3-MLL; B Lymphoblastic Leukemia; Blastic Plasmacytoid Dendritic Cell Neoplasm; Bone Marrow Examination and Techniques; Mast Cell Leukemia; Mixed Phenotype Acute Leukemia; Overview and Classification of Myelodysplastic Syndromes; Overview of Acute Myeloid Leukemia; Plasma Cell Myeloma; Refractory Anemia With Excess Blasts


    CD34


    hematopoietic progenitor cell antigen


    MY10, IOM34, QBEND10, 8G12, 1309, HPCA-1, NU-4A1, TUK4, clone 581, BI-3c5