Antibody Name/Symbol |
Antibody Description |
Clones/Alternative Names |
Chapters |
α-1-antichymotrypsin |
alpha 1 antichromotrypsin |
|
Calcifying Fibrous Tumor |
α-1-antitrypsin |
alpha 1 antitrypsin |
A1AT |
Yolk Sac Tumor |
α-fetoprotein |
alpha 1 fetoprotein |
AFP, Z5A06, Clone C3 |
Ependymoblastoma; Focal Nodular Hyperplasia; Hepatoblastoma; Hepatocellular Carcinoma; Juvenile Granulosa Cell Tumor; Mesenchymal Hamartoma; Pancreatoblastoma; Sertoli-Leydig Cell Tumors; Teratomas; Yolk Sac Tumor |
β-2-microglobulin |
|
B2-microglob |
Nodular Lymphocyte Predominant Hodgkin Lymphoma |
β-catenin |
beta catenin; involved in regulation of cell adhesion and in signal transduction through Wnt pathway |
B-catenin, CLONE 14, E-5, RB-9035Po, 17C2, 5H10 |
Adrenal Cortical Adenoma; Adrenal Cortical Carcinoma; Calcifying Fibrous Tumor; Craniopharyngioma; Desmoid Fibromatosis; Familial Adenomatous Polyposis; Fibroma; Fibromatosis Colli; Gardner Fibroma; Gastrointestinal Stromal Tumor; Hepatoblastoma; Infantile Fibrosarcoma; Infantile/ Juvenile Hyaline Fibromatosis; Inflammatory Myofibroblastic Tumor; Medulloblastoma; Myofibroma and Myofibromatosis; Nodular Fasciitis; Pancreatoblastoma; Papillary Thyroid Carcinoma; Pilomatricoma; Rhabdoid Tumor; Synovial Sarcoma; Wilms Tumor |
β-catenin-nuclear |
beta catenin nuclear |
|
Desmoid Fibromatosis; Familial Adenomatous Polyposis; Gardner Fibroma; Hemangiopericytoma |
β-tubulin |
beta tubulin |
B-tubulin, TUJ1 |
Pineal Parenchymal Tumors; Subependymal Giant Cell Tumor |
κ light chain |
kappa light chain |
KAPPA |
Autoimmune Lymphoproliferative Syndrome; Overview of Lymphoproliferative Disorders Associated with Primary Immune Deficiency |
λ light chain |
lambda light chain |
LAMBDA |
Autoimmune Lymphoproliferative Syndrome; Overview of Lymphoproliferative Disorders Associated with Primary Immune Deficiency |
ACTH |
adrenocorticotropic hormone |
|
Adrenal Cortical Adenoma |
Actin-HHF-35 |
actin, muscle (HHF35) |
MSA, HHF-35 |
Hemangiopericytoma; Infantile Fibrosarcoma; Kaposiform Hemangioendothelioma; Mucoepidermoid Carcinoma; Myofibroma and Myofibromatosis; Rhabdomyosarcoma |
Actin-sm |
actin, smooth muscle |
SMA, ASM-1, CGA7, 1A4, HUC1-1 |
Atypical Teratoid/Rhabdoid Tumor; Fibroma; Fibrous Umbilical Polyp; Gastrointestinal Stromal Tumor; Glomus Tumor; Hemangioma of Infancy; Hemangiopericytoma; Inclusion Body Fibromatosis; Infantile Fibromatosis; Infantile Fibrosarcoma; Inflammatory Myofibroblastic Tumor; Mesoblastic Nephroma; Myofibroma and Myofibromatosis; Neurothekeoma; Nodular Fasciitis; Pleomorphic Adenoma; Sialoblastoma |
AE1/AE3 |
mixture of 2 anticytokeratin clones that detect a variety of both high-and low-molecular weight cytokeratins |
|
Adamantinoma; Adrenal Cortical Carcinoma; Chordoma; Desmoplastic Small Round Cell Tumor; Glomus Tumor; Infantile Fibrosarcoma; Medulloblastoma; Melanotic Neuroectodermal Tumor of Infancy; MiTF/TFE Family Translocation-associated Carcinoma; Neuroendocrine Tumors; Papillary Thyroid Carcinoma; Pleuropulmonary Blastoma; Rhabdoid Tumor; Secretory Carcinoma; Thymoma |
AFP |
Alpha 1 fetoprotein |
α-fetoprotein, Z5A06, Clone C3 |
Gingival Granular Cell Tumor of the Newborn; Hepatoblastoma; Pancreatoblastoma; Pineal Parenchymal Tumors; Teratomas |
ALK |
anaplastic lymphoma kinase 1 |
ALK1, 5A4, ALKC |
Anaplastic Large Cell Lymphoma, ALK +; Calcifying Fibrous Tumor; Diffuse Large B-Cell Lymphoma; Inflammatory Myofibroblastic Tumor; Omental Mesenteric Hamartoma |
ALK1 |
anaplastic lymphoma kinase 1 |
5A4, ALKC |
Anaplastic Large Cell Lymphoma, ALK +; Calcifying Fibrous Tumor; Diffuse Large B-Cell Lymphoma; Inflammatory Myofibroblastic Tumor; Neuroblastoma and Ganglioneuroblastoma |
AMACR |
alpha-methylacyl-CoA racemase (AMACR) |
13H4, P504S |
MiTF/TFE Family Translocation-associated Carcinoma; Wilms Tumor |
Androgen receptor |
androgen receptor |
AR441, F39.4.1, AR-N20, ANDROGEN RE |
Gynecomastia Trichoepithelioma |
APC |
adenomatous polyposis coliprotein |
|
Desmoid Fibromatosis; Familial Adenomatous Polyposis; Gardner Fibroma |
Aromatase |
key enzyme in the byosynthesis of estrogen |
|
Gynecomastia |
Basic fibroblast growth factor |
|
FGF2, BFGF, BASIC FGF |
Intravascular Papillary Endothelial Hyperplasia |
Bcl-2 |
B-cell lymphoma 2; suppresses apoptosis in a variety of cell systems |
ONCL2, BCL2/100/D5, 124, 124.3 |
Anaplastic Large Cell Lymphoma, ALK+; Burkitt Lymphoma; Diffuse Large B-Cell Lymphoma; Fibrous Histiocytoma; Hemangiopericytoma; Nodular Lymphocyte Predominant Hodgkin Lymphoma; Pediatric Follicular Lymphoma; Synovial Sarcoma; Thymoma; Trichoepithelioma |
Bcl-6 |
B-cell CLL/lymphoma 6 |
LN22, GI191E/A8, N-3, PG-B6P, P1F6, 3FR-1 |
Burkitt Lymphoma; Classical Hodgkin Lymphoma; Diffuse Large B-Cell Lymphoma; Nodular Lymphocyte Predominant Hodgkin Lymphoma; Pediatric Follicular Lymphoma |
BER-EP4 |
epithelial cell adhesion molecule |
AUA1, VU-1D9, EPCAM, C10, HEA125 |
Trichoepithelioma |
BOB1 |
B-cell OCT-binding protein 1 |
SC955, BOB.1 |
Classical Hodgkin Lymphoma; Diffuse Large B-Cell Lymphoma; Nodular Lymphocyte Predominant Hodgkin; Lymphoma; Primary Mediastinal (Thymic) Large B-cell Lymphoma |
C-Kit |
C-kit; tyrosine-protein kinase activity |
CD117, C-19 (C-KIT), 104D2, 2E4, CKIT, A4502, H300, CMA-767 |
Desmoid Fibromatosis; Inflammatory Polyps; Mastocytosis |
CA9 |
carbonic anhydrase IX |
CAIX, ab1508, M75, NB100-417 |
MiTF/TFE Family Translocation-associated Carcinoma |
Calcitonin |
polypeptide hormone produced by parafollicular cells (C cells) of the thyroid |
CALBINDIN28 |
Follicular Adenoma; Medullary Thyroid Carcinoma; Neuroendocrine Tumors; Papillary Thyroid Carcinoma |
Caldesmon |
actin interacting and calmodulin binding protein found in smooth muscle and other cell types |
|
Myofibroma and Myofibromatosis |
Calponin |
thin filament-associated protein that is implicated in regulation and modulation of smooth muscle contraction |
N3, 26A11, CALP, CNN1, SMCC, Sm Calp |
Chondromyxoid Fibroma; Hemangiopericytoma; Inclusion Body Fibromatosis; Myofibroma and Myofibromatosis; Pleomorphic Adenoma |
Calretinin |
29 kDa calcium binding protein that is expressed in central and peripheral nervous system and in many normal and pathological tissues |
DAK-CALRET, 5A5, CAL 3F5, DC8, AB149 |
Adrenal Cortical Carcinoma; Juvenile Granulosa Cell Tumor; Sertoli-Leydig Cell Tumors; Synovial Sarcoma; Thecoma-Fibroma |
CAM5.2 |
cytokeratin 8/18 (CAM5.2) |
5D3, Zym5.2, 5D3, CAM 5.2, KER 10.11, NCL-5D3 |
Choroid Plexus Tumors |
Carcinoembryogenic antigen |
|
CEA-M, mCEA, CEA-B18, CEA-D14, CEAGOLD 1, T84.6, CEA-GOLD 2, CEA 11, CEA-GOLD 3, CEA 27, CEAGOLD 4, CEA 41, CEA-GOLD 5, T84.1, CEA-M, A5B7, CEJ065, IL-7, T84.66, TF3H8-1, 0062, D14, alpha-7, PARLAM 1, ZC23, CEM010, A115, COL-1, AF4, 12.140.10, 11-7, M773, CEA-M431_31, CEJO65 |
Medullary Thyroid Carcinoma; Syringoma; Teratomas |
CD1a |
T-cell surface glycoprotein |
JPM30, CD1A, O10, NA1/34 |
Chondroblastoma; Juvenile Xanthogranuloma; Langerhans Cell Histiocytosis; Thymoma |
CD2 |
T-cell surface antigen, LFA2 |
271, MT910, AB75, LFA-2 |
Anaplastic Large Cell Lymphoma, ALK +; Autoimmune Lymphoproliferative Syndrome; B Lymphoblastic Leukemia/ Lymphoma; Mastocytosis; Primary Mediastinal (Thymic) Large B-Cell Lymphoma |
CD3 |
T-cell receptor |
F7238, A0452, CD3-P, CD3-M, SP7, PS1 |
Anaplastic Large Cell Lymphoma, ALK +; Autoimmune Lymphoproliferative Syndrome; Classical Hodgkin Lymphoma; Desmoplastic Small Round Cell Tumor; Diffuse Large B-Cell Lymphoma; Nodular Lymphocyte Predominant Hodgkin Lymphoma; Overview of Lymphoproliferative Disorders Associated with Primary Immune Deficiency; Primary Mediastinal (Thymic) Large B-Cell Lymphoma; T Lymphoblastic Leukemia/ Lymphoma; Thymoma |
CD4 |
T-cell surface glycoprotein, L3T4 |
IF6, 1290, 4B12, 1F6, CD04 |
Acute Myeloid Leukemia; Anaplastic Large Cell Lymphoma, ALK+; Autoimmune Lymphoproliferative Syndrome; Burkitt Lymphoma; Classical Hodgkin Lymphoma; Diffuse Large B-Cell Lymphoma; Myeloid Sarcoma; T Lymphoblastic Leukemia/Lymphoma |
CD5 |
T-cell surface glycoprotein Leu1, T1 |
NCL-CD5, 4C7, 54/B4, 54/F6 |
Anaplastic Large Cell Lymphoma, ALK +; Autoimmune Lymphoproliferative Syndrome; Childhood Myelodysplastic Syndrome; T Lymphoblastic Leukemia/ Lymphoma; Thymoma |
CD7 |
T-cell antigen precursor Leu 9 |
272, CD7-272 |
Anaplastic Large Cell Lymphoma, ALK +; Autoimmune Lymphoproliferative Syndrome; B Lymphoblastic Leukemia/ Lymphoma; Diffuse Large B-Cell Lymphoma; Myeloid Sarcoma; T Lymphoblastic Leukemia/Lymphoma |
CD8 |
T-cell coreceptor antigen, Leu 2, T-cytotoxic cells |
M7103, C8/144, C8/144B |
Autoimmune Lymphoproliferative Syndrome; Primary Mediastinal (Thymic) Large B-Cell Lymphoma |
CD9 |
motility-related protein-1 (MRP-1) |
72F16, BA-2 |
Mastocytosis |
CD10 |
neutral endopeptidase |
NCL-270, CALLA, neprilysin, neutral endopeptidase, NEP |
B Lymphoblastic Leukemia/Lymphoma; Burkitt Lymphoma; Diffuse Large B-Cell Lymphoma; Hepatocellular Carcinoma; MiTF/TFE Family Translocation-associated Carcinoma; Pancreatoblastoma; Pediatric Follicular Lymphoma; Pleomorphic Adenoma; Primary Mediastinal (Thymic) Large B-Cell Lymphoma |
CD13 |
plays role in growth of DC/macrophage progenitors and precursors |
|
Acute Myeloid Leukemia; B Lymphoblastic Leukemia/Lymphoma; Childhood Myelodysplastic Syndrome |
CD14 |
coreceptor for lipopolysaccharide binding protein |
FMC32 |
Mastocytosis |
CD15 |
reacts with Reed-Sternberg cells of Hodgkin disease and with granulocytes |
VIM-2, 3C4, LEU-M1, TU9, VIM-D5, MY1, CBD1, MMA, 3CD1, C3D1, Lewis x, SSEA-1 |
Anaplastic Large Cell Lymphoma, ALK+; Childhood Myelodysplastic Syndrome; Classical Hodgkin Lymphoma; Diffuse Large B-Cell Lymphoma; Inflammatory Myofibroblastic Tumor; Nodular Lymphocyte Predominant Hodgkin Lymphoma |
CD16 |
Fc receptor of IgG |
|
Childhood Myelodysplastic Syndrome; Mastocytosis |
CD19 |
B-cell antigen |
|
B Lymphoblastic Leukemia/Lymphoma; Burkitt Lymphoma |
CD20 |
tumor necrosis factor SF8 |
BER-H2, KI-1, TNFRSF8 |
Anaplastic Large Cell Lymphoma, ALK +; Autoimmune Lymphoproliferative Syndrome; B Lymphoblastic Leukemia/ Lymphoma; Burkitt Lymphoma; Classical Hodgkin Lymphoma; Diffuse Large B-Cell Lymphoma; Myeloid Sarcoma; Nodular Lymphocyte Predominant Hodgkin Lymphoma; Overview of Lymphoproliferative Disorders Associated with Primary Immune Deficiency Pediatric Follicular Lymphoma; Primary Mediastinal (Thymic) Large B-Cell Lymphoma; T Lymphoblastic Leukemia/ Lymphoma; Thymoma |
CD21 |
CR2, complement component receptor 2, Epstein-Barr virus receptor |
IF8 |
Classical Hodgkin Lymphoma; Nodular Lymphocyte Predominant Hodgkin Lymphoma |
CD22 |
B-cell receptor |
FPC1, LEU 14 |
B Lymphoblastic Leukemia/Lymphoma; Burkitt Lymphoma; Classical Hodgkin Lymphoma; Diffuse Large B-Cell Lymphoma; Primary Mediastinal (Thymic) Large B-Cell Lymphoma |
CD23 |
Fc ε RII, low-affinity IgE receptor, IGEBF |
1B12, MHM6BU38 |
Primary Mediastinal (Thymic) Large B-Cell Lymphoma; Diffuse Large B-Cell Lymphoma |
CD25 |
If-2 receptor alpha |
2A3, 4C9 |
B Lymphoblastic Leukemia/Lymphoma; Hemophagocytic Syndrome; Mastocytosis |
CD30 |
tumor necrosis factor SF8 |
BER-H2, KI-1, TNFRSF8 |
Anaplastic Large Cell Lymphoma, ALK +; Classical Hodgkin Lymphoma; Diffuse Large B-Cell Lymphoma; Inflammatory Myofibroblastic Tumor; Langerhans Cell Histiocytosis; Nodular Lymphocyte Predominant Hodgkin Lymphoma; Primary Mediastinal (Thymic) Large B-Cell Lymphoma |
CD31 |
platelet endothelial cell adhesion molecule |
JC/70, JC/70A, PECAM-1 |
Cavernous Hemangioma; Glomus Tumor; Hemangioendothelioma; Hemangioma of Infancy; Kaposiform Hemangioendothelioma; Malignant Peripheral Nerve Sheath Tumor; Myeloid Proliferations Related to Down Syndrome; Pseudoangiomatous Stromal Hyperplasia; Spindle Cell Hemangioma; Tufted Angioma |
CD33 |
SIGLEC lectin 3 |
PWS44 |
Acute Myeloid Leukemia; B Lymphoblastic Leukemia/Lymphoma; Childhood Myelodysplastic Syndrome; Myeloid Sarcoma |
CD34 |
hematopoietic progenitor cell antigen |
MY10, IOM34, QBEND10, 8G12, 1309, HPCA-1, NU-4A1, TUK4, clone 581, BI-3c5 |
Acute Myeloid Leukemia; B Lymphoblastic Leukemia/Lymphoma; Calcifying Fibrous Tumor; Cavernous Hemangioma; Childhood Myelodysplastic Syndrome; Clear Cell Sarcoma; Desmoid Fibromatosis; Fibrous Umbilical Polyp; Gardner Fibroma; Gastrointestinal Stromal Tumor; Giant Cell Fibroblastoma/ Dermatofibrosarcoma Protuberans; Hemangioendothelioma; Hemangioma of Infancy; Hemangiopericytoma; Kaposiform Hemangioendothelioma; Malignant Melanoma; Myeloid Proliferations Related to Down Syndrome; Myeloid Sarcoma; Myofibroma and Myofibromatosis; Neurofibroma; Proliferative Fasciitis/Myositis; Pseudoangiomatous Stromal Hyperplasia; Rhabdoid Tumor; Synovial Sarcoma; T Lymphoblastic Leukemia/Lymphoma; Trichoepithelioma; Tufted Angioma |
CD38 |
acute lymphoblastic T-cell antigen |
SPC32, VS38, T10 |
Diffuse Large B-Cell Lymphoma |
CD42b |
platelet surface membrane glycoprotein that functions as a receptor for von Willebrand factor (VWF) |
glycoprotein 1b, GP lb |
Acute Myeloid Leukemia; Myeloid Proliferations Related to Down Syndrome |
CD43 |
major sialoglycoprotein on surface of human T lymphocytes, monocytes, granulocytes, and some B lymphocytes |
LEU-22, DF-T1, L60, MT1, sialophorin, leukosialin, SPN |
Burkitt Lymphoma; Myeloid Sarcoma |
CD44 |
CD 44 (cell adhesion receptor for hyaluronic acid HCAM) |
HCAM, CD44H, B-F24, A3D8, 2C5, CD44S, F10-44.2, 156-3C11, DF1485, BBA10, VFF-14, CD44V10, CD44V3, 3G5, CD44V3-10-P, CD44V3-10, 3D2, CD44V4_5, CD44V5, VFF-8, VFF-7, 2F10, VFF-18, CD44V6, CD44V7, VFF-9, CD44V7_8, VFF-17 |
Burkitt Lymphoma |
CD45 |
leukocyte common antigen |
LCA, PD7/26, 1.22/4.14, T29/33, RP2/18, PD7, 2D1, 2B11+PD7/26 |
Anaplastic Large Cell Lymphoma, ALK+; B Lymphoblastic Leukemia/Lymphoma; Classical Hodgkin Lymphoma; Desmoplastic Small Round Cell Tumor; Diffuse Large B-Cell Lymphoma; Ewing Sarcoma; Nodular Lymphocyte Predominant Hodgkin Lymphoma; Primary Mediastinal (Thymic) Large B-Cel l Lymphoma; Retinoblastoma |
CD45RA |
isoform of CD45 expressed by naive T cells |
4KB5, MT2, CD45RA, MB1 |
Autoimmune Lymphoproliferative Syndrome |
CD45RO |
isoform of CD45 located on memory T cells |
ICH1-L, low molecular weight isoform LCA |
Autoimmune Lymphoproliferative Syndrome |
CD56 |
NCAM (neutral cellular adhesion molecule) |
MAB735, ERIC-1, 25-KD11, 123C3, 24-MB2, BC56C04, 1B6, 14-MAB735, NCC-LU-243, MOC-1, NCAM |
Diffuse Large B-Cell Lymphoma; Neuroblastoma and Ganglioneuroblastoma; Neuroendocrine Tumors; Synovial Sarcoma |
CD57 |
β-1, 3-glucuronyltransferase 1 (glucuronosyltransferase P) |
LEU-7, NK1, HNK-1, TB01, B3GAT1 |
Diffuse Large B-Cell Lymphoma; Melanotic Neuroectodermal Tumor of Infancy; Neuroendocrine Tumors; Neurothekeoma; Nodular Lymphocyte Predominant Hodgkin Lymphoma; Wilms Tumor |
CD61 |
cluster of differentiation found on thrombocytes corresponding to glycoprotein IIb/IIIa |
Integrin, beta 3 (platelet glycoprotein IIIa), ITGB3, GP3A, GPIIIa, Y2/5, HPA |
Acute Myeloid Leukemia; Childhood Myelodysplastic Syndrome; Myeloid Proliferations Related to Down Syndrome |
CD63 |
tetraspan intracellular granule protein |
NKI/C3, basophil activation test in allergy |
Giant Cell Fibroblastoma/Dermatofibrosarcoma Protuberans; Neurothekeoma |
CD68 |
cytoplasmic granule protein of monocytes, macrophages |
PG-M1, KP-1 |
Fibrous Histiocytoma; Gingival Granular Cell Tumor of the Newborn; Juvenile Myelomonocytic Leukemia; Juvenile Xanthogranuloma; Myeloid Sarcoma; Proliferative Fasciitis/Myositis |
CD71 |
protein required for iron delivery from transferrin to cells |
transferrin receptor protein 1 (TfR1) |
Acute Myeloid Leukemia; Childhood Myelodysplastic Syndrome |
CD79-a |
immunoglobulin-associated alpha, MB1 |
MB-1, 11D10, 11E3, CD79A, HM47/A9, HM57, JCB117, CD79a, CD79-a |
Anaplastic Large Cell Lymphoma, ALK +; Diffuse Large B-Cell Lymphoma; Primary Mediastinal (Thymic) Large B-Cell Lymphoma |
CD79-α |
immunoglobulin-associated alpha, MB1 |
MB-1, 11D10, 11E3, CD79A, HM47/ A9, HM57, JCB117, CD79a, CD79-α |
Burkitt Lymphoma; Classical Hodgkin Lymphoma; Ewing Sarcoma; Primary Mediastinal (Thymic) Large B-Cell Lymphoma |
CD95 |
fatty acid synthase; plays a role in regulating apoptosis |
FAS, APO-1, CD95, UB2, B-10, FAS |
Autoimmune Lymphoproliferative Syndrome |
CD99 |
cell surface glycoprotein for migration, T cell adhesion, MIC2 |
CD99-MEMB, MIC2, 12E7, HBA71, O13, P30/32MIC2, M3601 |
Anaplastic Large Cell Lymphoma, ALK +; Burkitt Lymphoma; Desmoplastic Small Round Cell Tumor; Ewing Sarcoma; Inclusion Body Fibromatosis; Juvenile Granulosa Cell Tumor; Neuroblastoma and Ganglioneuroblastoma; Primitive Neuroectodermal Tumor; Rhabdomyosarcoma; Synovial Sarcoma; Teratomas; Thymoma |
CD117 |
C-kit, tyrosine-protein kinase activity |
C-19 (C-KIT), 104D2, 2E4, C-KIT, A4502, H300, CMA-767 |
Acute Myeloid Leukemia; Calcifying Fibrous Tumor; Choroid Plexus Tumor; Childhood Myelodysplastic Syndrome; Dysgerminoma; Gastrointestinal Stromal Tumor; Gonadoblastoma; Infantile Fibromatosis; Inflammatory Myofibroblastic Tumor; Mastocytosis; Myeloid Proliferations Related to Down Syndrome; Pleomorphic Adenoma; Secretory Carcinoma; Thymoma |
CD138 |
syndecan; a useful marker for plasma cells |
B-B4, AM411-10M, MI15 |
Anaplastic Large Cell Lymphoma, ALK+; Burkitt Lymphoma; Diffuse Large B-Cell Lymphoma |
CD163 |
macrophage hemoglobin scavenging system |
10D6 |
Acute Myeloid Leukemia |
CD271 |
nerve growth factor receptor |
ME 20.4, MS-394-P1, P75NGFR, NGFR5, P75NTR |
Giant Cell Fibroblastoma/Dermatofibrosarcoma Protuberans |
CD303 |
monoclonal antibody directed toward immature plasmacytoid dendritic cells |
BDCA-2 |
Myeloid Sarcoma |
CEA-M |
carcinoembryonic antigen, monoclonal |
CEA-B18, CEA-D14, CEA-GOLD 1, T84.6, CEA-GOLD 2, CEA 11, CEA-GOLD 3, CEA 27, CEA-GOLD 4, CEA 41, CEA-GOLD 5, T84.1, CEA-M, A5B7, CEJ065, IL-7, T84.66, TF3H8-1, 0062, D14, alpha-7, PARLAM 1, ZC23, CEM010, A115, COL-1, AF4, 12.140.10, 11-7, M773, CEA-M431_31, CEJO65, mCEA |
Follicular Adenoma; Medullary Thyroid Carcinoma |
CEA-P |
carcinoembryonic antigen, polyclonal |
|
Hepatocellular Carcinoma; Medullary Thyroid Carcinoma; Yolk Sac Tumor |
Chromogranin-A |
pituitary secretory protein 1 |
PHE-5, PHE5, E001, DAK-A3 |
Medullary Thyroid Carcinoma; Follicular Adenoma; Islet Cell Adenoma; Medullary Thyroid Carcinoma; Neuroendocrine Tumors; Pancreatoblastoma |
Chymase |
serine protease found in mast cells and basophils; acts as a mediator of inflammation |
|
Mastocytosis |
Chymotrypsin |
digestive enzyme synthesized in pancreas, involved in proteolysis |
|
Pancreatoblastoma |
CITED-1 |
melanocyte specific gene 1 antibody, CBP/P300-interacting transactivator 1 |
J72220K, MSG1 |
Follicular Adenoma; Papillary Thyroid Carcinoma |
CK-PAN |
cytokeratin-pan (AE1/AE3/LP34); cocktail of high and low molecular weight cytokeratins |
keratin pan, MAK-6, K576, LU-5, KL-1, KC-8, MNF 116, pankeratin, pancytokeratin |
Follicular Adenoma; Gingival Granular Cell Tumor of the Newborn; Mucoepidermoid Carcinoma; Myofibroma and Myofibromatosis; Pancreatoblastoma; Pleomorphic Adenoma; Sialoblastoma; Synovial Sarcoma; T Lymphoblastic Leukemia/Lymphoma; Thecoma-Fibroma; Yolk Sac Tumor |
CK5/6 |
cytokeratin 5/6, high molecular weight cytokeratins |
D5/16 B4 |
Mucoepidermoid Carcinoma |
CK7 |
cytokeratin 7, low molecular weight cytokeratin |
K72.7, KS7.18, OVTL 12/30, LDS-68, CK 07 |
Craniopharyngioma; MiTF/TFE Family Translocation-associated Carcinoma; Mucoepidermoid Carcinoma; Papillary Thyroid Carcinoma; Pleomorphic Adenoma; Sertoli-Leydig Cell Tumors; Synovial Sarcoma Wilms Tumor |
CK8 |
cytokeratin 8 |
K8.8, 4.1.18, TS1, C-51, M20 |
Craniopharyngioma |
CK10 |
cytokeratin 10 |
LHP1, DE-K10, RKSE60 |
Syringoma |
CK14 |
cytokeratin 14, high molecular weight cytokeratin |
LL002 |
Mucoepidermoid Carcinoma |
CK8/18/CAM5.2 |
cytokeratin 8/18; simple epithelial-type cytokeratins |
5D3, Zym5.2, CAM 5.2, KER 10.11, NCL-5D3, cytokeratin LMW |
Follicular Adenoma; Islet Cell Adenoma; Neuroendocrine Tumors; Rhabdoid Tumor |
CK17 |
cytokeratin 17 |
E3 |
Mucoepidermoid Carcinoma |
CK18 |
cytokeratin 18 |
M9, DC-10, CY-90, KS18.04 |
MiTF/TFE Family Translocation-associated Carcinoma |
CK19 |
cytokeratin 19, low molecular weight cytokeratin |
BA17, RCK108, LP2K, B170, A53-BA2, KS19.1, 170.2.14 |
Follicular Adenoma; Follicular Carcinoma; Mucoepidermoid Carcinoma; Pancreatoblastoma; Papillary Thyroid Carcinoma; Sialoblastoma; Synovial Sarcoma; Thymoma |
CK20 |
cytokeratin 20, low molecular weight cytokeratin |
KS20.8 |
Craniopharyngioma; Mucoepidermoid Carcinoma; Papillary Thyroid Carcinoma; Pleomorphic Adenoma |
Clusterin |
clusterin, alpha chain specific |
41D, E5 |
Anaplastic Large Cell Lymphoma, ALK+ |
Collagen II |
major component of articular and hyaline cartilage |
2B1.5 |
Chondromyxoid Fibroma |
Collagen IV |
major constituent of the basement membranes along with laminins, proteoglycans, and enactins |
CIV22, COL4A [1-5], collagen α-1(IV) chain |
Chondromyxoid Fibroma; Gastrointestinal Stromal Tumor; Giant Cell Fibroblastoma/Dermatofibrosarcoma Protuberans; Glomus Tumor; Hemangiopericytoma; Medulloepithelioma; Neurofibroma |
Cyclin-D1 |
protein with important cell cycle regulatory functions |
bcl-1 (cyclin D1) A-12, PRAD1, AM29, DCS-6, SP4, 5D4, D1GM, P2D11F11, CCND1Cyl-1 |
Papillary Thyroid Carcinoma; Pediatric Follicular Lymphoma |
Cytokeratin |
|
|
Papillary Thyroid Carcinoma; Pediatric Follicular Lymphoma; Chondroblastoma; Clear Cell Sarcoma; Craniopharyngioma; Desmoplastic Small Round Cell Tumor; Ependymoma; Glioblastoma; Glomus Tumor; Juvenile Granulosa Cell Tumor; Malignant Melanoma; Medullary Thyroid Carcinoma Medulloblastoma; Medulloepithelioma; Neuroendocrine Tumors; Oligodendroglioma; Phyllodes Tumor; Pleomorphic Adenoma; Rhabdomyosarcoma; Secretory Carcinoma; Sialoblastoma; Synovial Sarcoma; T Lymphoblastic Leukemia/ Lymphoma; Thymoma; Wilms Tumor |
Cytokeratin 14 |
high molecular weight cytokeratin |
LL002 |
Pleomorphic Adenoma; Secretory Carcinoma |
Cytokeratin 19 |
low molecular weight cytokeratin |
BA17, RCK108, LP2K, B170, A53-BA2, KS19.1, 170.2.14 |
Papillary Thyroid Carcinoma |
Cytokeratin 20 |
low molecular weight cytokeratin |
KS20.8 |
T Lymphoblastic Leukemia/Lymphoma |
Cytokeratin 5/6 |
high molecular weight cytokeratins |
D5/16 B4 |
Secretory Carcinoma |
Cytokeratin 8/18 |
simple epithelial-type cytokeratins |
5D3, Zym5.2, CAM 5.2, KER 10.11, NCL-5D3, cytokeratin LMW |
Secretory Carcinoma |
D2-40 |
reacts with an O-linked sialoglycoprotein found on lymphatic endothelium |
podoplanin, M2A, D2-40 |
Kaposiform Hemangioendothelioma |
Desmin |
class III intermediate filaments found in muscle cells |
M760, DE-R-11, D33, DE5, DE-U-10, ZC18 |
Atypical Teratoid/Rhabdoid Tumor; Botryoid Rhabdomyosarcoma; Calcifying Fibrous Tumor; Clear Cell Sarcoma; Desmoid Fibromatosis; Desmoplastic Small Round Cell Tumor; Ewing Sarcoma; Fetal Rhabdomyoma; Fibroma; Fibrous Hamartoma of Infancy; Fibrous Histiocytoma; Fibrous Umbilical Polyp; Gastrointestinal Stromal Tumor; Gingival Granular Cell Tumor of the Newborn; Glomus Tumor; Hemangiopericytoma; Inclusion Body Fibromatosis; Infantile Fibromatosis; Infantile Fibrosarcoma; Inflammatory Myofibroblastic Tumor; Malignant Melanoma; Malignant Peripheral Nerve Sheath Tumor; Medulloblastoma; Mesoblastic Nephroma; Myeloid Sarcoma; Myofibroma and Myofibromatosis; Omental Mesenteric Hamartoma; Pleuropulmonary Blastoma; Primitive Neuroectodermal Tumor; Proliferative Fasciitis/Myositis; Rhabdoid Tumor; Rhabdomyoma; Rhabdomyosarcoma; Synovial Sarcoma; Thymoma; Wilms Tumor |
DOG1 |
transmembrane protein 16A |
DOG1 (TMEM16A), DOG 1.1 |
Gastrointestinal Stromal Tumor |
DPC4 |
mothers against DPP homolog 4 |
MADR1 JV4-1, DPC4_SMAD4, SMAD4, B-8 |
Gastrointestinal Stromal Tumor |
E-cadherin |
epithelial calcium dependent adhesion molecule |
36B5, ECH-6, ECCD-2, CDH1, 5H9, NCH 38, Clone 36, 4A2 C7, E9, 67A4, HECD-1, SC-8426 |
Giant Cell Fibroblastoma/Dermatofibrosarcoma Protuberans; MiTF/TFE Family Translocation-associated Carcinoma; Secretory Carcinoma |
EBER |
Epstein-Barr virus encoded RNA |
|
Burkitt Lymphoma; Nodular Lymphocyte Predominant Hodgkin Lymphoma; Primary Mediastinal (Thymic) Large B-Cell Lymphoma |
EBNA2 |
Epstein-Barr virus-associated nuclear antigen 2 |
|
Burkitt Lymphoma |
EBV-LMP |
Epstein-Barr virus latent membrane protein |
LMP1, CS 1-4 |
Burkitt Lymphoma; Classical Hodgkin Lymphoma; Nodular Lymphocyte Predominant Hodgkin Lymphoma; Primary Mediastinal (Thymic) Large B-Cell Lymphoma |
EGFR |
v-erb b1 erythroblastic leukemia viral gene, epidermal growth factor receptor |
2-18C9, EGFR1, EGFR PHRMDX, NCL-R1, H11, C-ERBB-1, E30, EGFR.113, 31G73C6, 2-18C9 |
Glioblastoma; Secretory Carcinoma |
EMA |
epithelial membrane antigen |
GP1.4, 214D4, MC5, E29, MUC1, EMA/MUC1 |
Adrenal Cortical Carcinoma; Anaplastic Large Cell Lymphoma, ALK+; Atypical Teratoid/Rhabdoid Tumor; Choroid Plexus Tumors; Classical Hodgkin Lymphoma; Diffuse Large B-Cell Lymphoma; Ependymoma; Ewing Sarcoma; Fibrous Umbilical Polyp; Glioblastoma; Glomus Tumor; Hemangiopericytoma; Medulloblastoma; Medulloepithelioma; Meningioangiomatosis; Neurofibroma; Neurothekeoma; Nodular Lymphocyte Predominant Hodgkin Lymphoma; Oligodendroglioma; Pineal Parenchymal Tumors; Primary Mediastinal (Thymic) Large B-Cell Lymphoma; Primitive Neuroectodermal Tumor; Rhabdomyosarcoma; Synovial Sarcoma; Syringoma |
EMA/MUC1 |
epithelial membrane antigen |
EMA, GP1.4, 214D4, MC5, E29, MUC1, LICRLON-M8, BC3, DF3, VU3D1, MUSEII, RD-1, MA695, MA552, PS2P446, 115D8, MUC1, MAM6, CA15.3, MUC01 |
Anaplastic Large Cell Lymphoma, ALK +; Atypical Teratoid/Rhabdoid Tumor; Choroid Plexus Tumors; Dysgerminoma; MiTF/TFE Family Translocation-associated Carcinoma; Neurofibroma; Neurothekeoma; Rhabdoid Tumor; Sertoli-Leydig Cell Tumors; Synovial Sarcoma; Thecoma-Fibroma; Yolk Sac Tumor |
EpCAM/BER-EP4/CD326 |
epithelial cell adhesion molecule |
AUA1, VU-1D9, EPCAM, C10, HEA125, BER-EP4 |
Choroid Plexus Tumors; Mucoepidermoid Carcinoma |
Epithelial membrane antigen |
|
EMA, GP1.4, 214D4, MC5, E29, MUC1, LICRLON-M8, BC3, DF3, VU3D1, MUSEII, RD-1, MA695, MA552, PS2P446, 115D8, MUC1, MAM6, CA15.3, MUC01 |
Anaplastic Large Cell Lymphoma, ALK+; Chordoma; Ependymoma; Fibrolipomatous Hamartoma of Nerve; MiTF/TFE Family Translocation-associated Carcinoma; Sialoblastoma |
Epstein-Barr virus encoded RNA |
|
EBER |
Autoimmune Lymphoproliferative Syndrome |
ER |
estrogen receptor protein |
1D5, 6F11, SP1, 15D, H222, TE111, ERP, ER1D5, NCLER611, NCL-ER-LH2, PGP-1A6 |
Pleomorphic Xanthoastrocytoma; Gingival Granular Cell Tumor of the Newborn; Secretory Carcinoma |
ERP |
estrogen receptor protein |
1D5, 6F11, SP1, 15D, H222, TE111, ER, ER1D5, NCLER611, NCL-ER-LH2, PGP-1A6 |
Secretory Carcinoma |
Erythropoietin |
|
EPO |
Acute Myeloid Leukemia |
Factor XIIIa |
fibrin stabilizing factor |
FXIIIA |
Nodular Fasciitis |
FAS |
fatty acid synthase |
CD95/fas |
Autoimmune Lymphoproliferative Syndrome; Overview of Lymphoproliferative Disorders Associated with Primary Immune Deficiency |
FASL |
fatty acid synthase ligand |
CD95L, G247-4, CD95-L, FAS-L, TNFSF6 |
Autoimmune Lymphoproliferative Syndrome |
FAS ligand |
fatty acid synthase ligand |
CD95L, G247-4, CD95-L, FAS-L, TNFSF6, FASL |
Autoimmune Lymphoproliferative Syndrome; Overview of Lymphoproliferative Disorders Associated with Primary Immune Deficiency |
Fibrinogen |
soluble plasma glycoprotein made by the liver and involved in blood coagulation |
|
Hemaphagocytic Syndrome |
FLI-1 |
Friend leukemia virus integration 1 |
EWSR2, GI146-222, SC356, FLK-1, FLT-1 |
Hemophagocytic Syndrome; Ewing Sarcoma; Kaposiform Hemangioendothelioma; Synovial Sarcoma |
FVIIIRAg |
factor VIII-related-antigen |
FVIIIRAG, F8/86, von Willebrand factor |
Clear Cell Sarcoma; Hemangioendothelioma; Hemangioma of Infancy |
G-CSF |
granulocyte colony stimulating factor |
AB-1 |
Acute Myeloid Leukemia |
Galectin-3 |
|
NCL-GAL3, B2C10, 9C4 |
Follicular Adenoma; Papillary Thyroid Carcinoma |
Gastrin |
hormone released by G cells in stomach, duodenum, and pancreas that stimulates secretion of gastric acid (HCl) by parietal cells of stomach |
|
Islet Cell Adenoma |
GCDFP-15 |
gross cystic fluid protein 15 |
SABP, GPIP4, Gp17, 23A3, BRST-2, D6 (GROSS CYSTIC DISEASE FLUID PROTEIN) |
Secretory Carcinoma |
GFAP |
intermediate filament expressed by numerous cells of the CNS |
6F2, M761, GA-51, GFP-8A |
Anaplastic Astrocytoma; Atypical Teratoid/Rhabdoid Tumor; Choroid Plexus Tumors; Diffuse Astrocytoma (Low Grade); Ependymoma; Ganglion Cell Tumors; Glioblastoma; Heterotopic Neuroglial Tissue; Medulloblastoma; Mucoepidermoid Carcinoma; Neurofibroma; Neurothekeoma; Oligodendroglioma; Pilocytic Astrocytoma; Pleomorphic Adenoma; Pleomorphic Xanthoastrocytoma; Primitive Neuroectodermal Tumor; Retinoblastoma; Subependymal Giant Cell Tumor; Teratomas |
GH |
growth hormone |
HGH, hGH |
Craniopharyngioma; Follicular Carcinoma Pyogenic GranulomaChordoma |
Glial fibrillary acidic protein |
intermediate filament expressed by numerous cells of the CNS |
GFAP, 6F2, M761, GA-51, GFP-8A |
Ependymoma; Pleomorphic Adenoma; Sertoli-Leydig Cell Tumors |
Glucagon |
hormone secreted by the pancreas; functions to increase blood glucose levels |
|
Islet Cell Adenoma; Nesidioblastosis; Pancreatoblastoma |
Glypican-3 |
heparan sulfate proteoglycan with elevated expression in hepatocellular carcinoma |
1G12, GPC3 |
Hepatocellular Carcinoma |
GM-CSF |
granulocyte macrophage colony stimulating factor |
3209.1 |
Juvenile Myelomonocytic Leukemia |
Granulocyte colony stimulating factor |
granulocyte macrophage colony stimulating factor |
3209.1, GM-CSF |
Acute Myeloid Leukemia |
Granzyme B |
neutral serine protease |
GZM-B, 11F1, GR-B7 |
Anaplastic Large Cell Lymphoma, ALK+ |
Growth hormone |
|
GH, HGH, hGH |
Craniopharyngioma; Pyogenic Granuloma |
H-caldesmon |
|
High molecular weight caldesmon, H-CD |
Chrondromyxoid Fibroma; Synovial Sarcoma |
HBME-1 |
mesothelioma antibody |
|
Follicular Adenoma; Follicular Carcinoma; Papillary Thyroid Carcinoma |
HCAD |
H-caldesmon (high molecular weight caldesmon) |
H-CD |
Hemangiopericytoma; Synovial Sarcoma |
HCG |
human chorionic gonadotropin |
|
Craniopharyngioma; Dysgerminoma; Gynecomastia; Pineal Parenchymal Tumors |
Hep-Par1 |
hepatocyte paraffin 1 |
OCH1E5.2.10, HEPPAR1 |
Hepatocellular Carcinoma |
HER2 |
v-erb-b2 erythroblastic leukemia viral gene protein, human epidermal growth factor receptor 2 |
c-erb-B2, HER2/neu, NEU, HER-2, NCL-CBE1, 10A7, 9G6.10, SP3, 4B5, epidermal growth factor receptor 2, P185, 9G6.20, A0485, C-ERBB-2, CB11, ERBB-2, 3B5, TAB250, HERCEPTEST, E2-4001, HER-2_NEU |
Mucoepidermoid Carcinoma; Secretory Carcinoma |
HMB-45 |
monoclonal antibody that reacts against an antigen present in melanocytic tumors |
|
Blue Nevus; Glomus Tumor; Malignant Melanoma; Malignant Peripheral Nerve Sheath Tumor; Medulloblastoma; Melanotic Neuroectodermal Tumor of Infancy; MiTF/TFE Family Translocation-associated Carcinoma Schwannoma |
Human chorionic gonadotropin |
|
HCG, hCG |
Craniopharyngioma; Dysgerminoma; Gynecomastia; Teratomas |
IgA |
immunoglobin A |
|
Anaplastic Large Cell Lymphoma, ALK +; Autoimmune Lymphoproliferative Syndrome |
IgD |
immunoglobulin D |
|
Nodular Lymphocyte Predominant Hodgkin Lymphoma |
IGF-1 |
insulin growth factor-like 1 |
I-5C9 |
Craniopharyngioma; Medulloepithelioma |
IGF-2 |
insulin growth factor-like 2 |
W2-H1 |
Adrenal Cortical Carcinoma |
IgG |
immunoglobulin G |
IGG |
Autoimmune Lymphoproliferative Syndrome |
IgM |
immunoglobulin M |
IGM |
Autoimmune Lymphoproliferative Syndrome; Burkitt Lymphoma; Overview of Lymphoproliferative Disorders Associated with Primary Immune Deficiency |
IL-7 |
stimulates differentiation of pluripotent hematopoietic stem cells into lymphoid progenitor cells; important for T-cell development |
Interleukin 7, Il7 |
Classical Hodgkin Lymphoma |
IL-13 |
interleukin 13 |
|
Classical Hodgkin Lymphoma; Primary Mediastinal (Thymic) Large B-Cell Lymphoma |
Immunoglobulin A |
|
IgA, IGA |
Autoimmune Lymphoproliferative Syndrome; Overview of Lymphoproliferative Disorders Associated with Primary Immune Deficiency |
Inhibin |
hormone released from testes or ovaries that down-regulates FSH synthesis and secretion |
R1, beta A subunit, INHIBIN |
Adrenal Cortical Carcinoma; Gonadoblastoma; Juvenile Granulosa Cell Tumor; Sertoli-Leydig Cell Tumors; Thecoma-Fibroma |
Inhibin-α |
produced by ovarina granulosa cells; inhibits production or secretion of pituitary gonadotropins, a sensitive marker for majority of sex cord-stromal tumors |
|
Adrenal Cortical Carcinoma |
INI1 |
member of SWI/SNF chromatin remodeling complex |
BAF47/SNF5, SNF5 |
Atypical Teratoid/Rhabdoid Tumor; Choroid Plexus Tumors; Mesoblastic Nephroma; Rhabdoid Tumor |
Intermediate filament |
neurofilament triplet protein |
|
Medulloblastoma |
IRF-4 |
interferon regulatory factor 4 |
MUM1P, clone MUM1, MUM1-IRF.4, MUM1, M17 |
Burkitt Lymphoma; Classical Hodgkin Lymphoma; Primary Mediastinal (Thymic) Large B-Cell Lymphoma |
JC virus |
type of human polyomavirus genetically similar to BK virus and SV-40 |
John Cunningham virus |
Diffuse Astrocytoma (Low Grade) |
Keratin-Pan |
cytokeratin-pan (AE1/AE3/LP34); cocktail of high and low molecular weight cytokeratins |
keratin pan, MAK-6, K576, LU-5, KL-1, KC-8, MNF 116, pankeratin, pancytokeratin, CKPAN |
Pleomorphic Adenoma; Synovial Sarcoma |
Kappa light chain |
|
KAPPA, κ light chain |
Autoimmune Lymphoproliferative Syndrome |
Ki-67 |
Ki-67 (MIB-1); marker of cell proliferation |
MMI, KI88, IVAK-2, MIB1 |
Adrenal Cortical Adenoma; Adrenal Cortical Carcinoma; Anaplastic Astrocytoma; Anaplastic Large Cell Lymphoma, ALK+; Atypical Teratoid/ Rhabdoid Tumor; Autoimmune Lymphoproliferative Syndrome; Burkitt Lymphoma; Choroid Plexus Tumors; Clear Cell Sarcoma; Craniopharyngioma; Diffuse Astrocytoma (Low Grade); Diffuse Large B-Cell Lymphoma; Ganglion Cell Tumors; Glioblastoma; Infantile Fibrosarcoma; Laryngotracheal Papillomatosis; Medulloblastoma; Mucoepidermoid Carcinoma; Nodular Lymphocyte Predominant Hodgkin Lymphoma; Oligodendroglioma; Pediatric Follicular Lymphoma; Pineal Parenchymal Tumors; Primitive Neuroectodermal Tumor; Synovial Sarcoma; T Lymphoblastic Leukemia/ Lymphoma |
KI-M1P |
marker of monocytes/macrophages |
|
Fibrous Histiocytoma; Giant Cell Fibroblastoma/Dermatofibrosarcoma Protuberans |
KP-1 |
cytoplasmic granule protein of monocytes, macrophages |
CD68, PG-M1 |
Oligodendroglioma |
Lambda light chain |
|
λ light chain, LAMBDA |
Autoimmune Lymphoproliferative Syndrome |
Laminin |
major protein in basal lamina |
LAMININ-4C7, 4C12.8, LAM-89 |
Ganglion Cell Tumors; Gastrointestinal Stromal Tumor; Gingival Granular Cell Tumor of the Newborn; Glomus Tumor |
LCA |
leukocyte common antigen |
PD7/26, 1.22/4.14, T29/33, CD45RB, RP2/18, CD45, PD7, 2D1, 2B11+PD7/26 |
Glioblastoma; Rhabdomyosarcoma |
Leptin |
|
LEP |
Gynecomastia |
LEU-7 |
β-1, 3-glucuronyltransferase 1 (glucuronosyltransferase P) |
CD57, NK1, HNK-1, TB01, B3GAT1 |
Oligodendroglioma |
Leukocyte common antigen |
|
LCA, PD7/26, 1.22/4.14, T29/33, CD45RB, RP2/18, CD45, PD7, 2D1, 2B11+PD7/26 |
Dysgerminoma |
Lewis-Y |
Lewis blood group antigen Y |
BR-96, LEWIS-Y, BG8, 77/180, F3 |
Kaposiform Hemangioendothelioma |
LH |
lutenizing hormone |
beta-LH |
Mucoepidermoid Carcinoma |
Lipase |
pancreatic lipase |
|
Islet Cell Adenoma |
LMP1 |
Epstein-Barr virus latent membrane protein |
EBV-LMP, CS 1-4 |
Burkitt Lymphoma |
Lutenizing hormone |
|
beta-LH |
Craniopharyngioma |
Lysozyme |
1, 4-beta N-acetylmuramidase C |
Lyz, Lzm, Ec3.2.1.17 |
Juvenile Myelomonocytic Leukemia; Myeloid Sarcoma; T Lymphoblastic Leukemia/Lymphoma |
Mart-1 |
mart-1 clone of Melan A |
|
Gastrointestinal Stromal Tumor; Malignant Melanoma |
MDM2 |
murine double minute oncogene (mdm2) |
HDM2, IF2, 2A10, 1B10, SMP14, murine double minute 2 |
Ependymoma; Osteosarcoma |
Melan-A |
melanoma antigen recognized by T cells 1 (MART-1); protein found on melanocytes; melanocyte differentiation antigen |
M2-7C10, CK-MM |
Blue Nevus; Glomus Tumor; Malignant Melanoma; Malignant Peripheral Nerve Sheath Tumor; Neuroendocrine Tumors |
met |
met proto-oncogene |
8F11, C-28, C-MET |
Giant Cell Tumor; Mastocytosis; Medullary Thyroid Carcinoma |
MIB1 |
Ki-67 (MIB1); marker of cell proliferation |
MMI, KI88, IVAK-2, MIB1 |
Ganglion Cell Tumors |
MIC2 |
cell surface glycoprotein for migration, T cell adhesion, MIC2 |
CD99, CD99-MEMB, MIC2, 12E7, HBA71, O13, P30/32MIC2, M3601 |
Primitive Neuroectodermal Tumor |
MK |
neurite growth promoting factor 2 |
MIDKINE, MK1 |
Pleuropulmonary Blastoma |
MMP-2 |
Matrix metalloproteinase 1 |
41-1E5, F-67, 3B6 |
Giant Cell Fibroblastoma/Dermatofibrosarcoma Protuberans |
MPO |
myeloperoxidase |
|
Acute Myeloid Leukemia; Myeloid Sarcoma |
MSA |
actin, smooth muscle |
actin-sm, ASM-1, CGA7, 1A4, HUC1-1 |
Myofibroma and Myofibromatosis |
MSG1 |
melanocyte specific gene 1 antibody |
CITED-1, J72220K |
Papillary Thyroid Carcinoma |
MT |
metallothionein |
CLONE E9 |
Follicular Carcinoma; Gingival Granular Cell Tumor of the Newborn; Juvenile Granulosa Cell Tumor; Medulloblastoma |
MUC1 |
epithelial membrane antigen |
LICR-LON-M8, BC3, DF3, VU3D1, MUSEII, RD-1, MA695, MA552, PS2P446, 115D8 |
Anaplastic Large Cell Lymphoma, ALK+ |
MUM1 |
Interferon regulatory factor 4 |
IRF-4, MUM1P, clone MUM1, MUM1-IRF.4, M17 |
Anaplastic Large Cell Lymphoma, ALK+; Diffuse Large B-Cell Lymphoma |
Myeloperoxidase |
|
MPO |
Acute Myeloid Leukemia; Childhood Myelodysplastic Syndrome; Mastocytosis; Myeloid Sarcoma |
MYOD1 |
myogenic differentiation 1 |
5.8A, 5.2F |
Botryoid Rhabdomyosarcoma; Fetal Rhabdomyoma; Infantile Fibrosarcoma; Myeloid Sarcoma; Rhabdomyosarcoma; Wilms Tumor |
Myogenin |
|
F5D, MYF3, MYF4, MYOGENIN, LO26 |
Botryoid Rhabdomyosarcoma; Desmoplastic Small Round Cell Tumor; Ewing Sarcoma; Fetal Rhabdomyoma; Fibroma; Infantile Fibrosarcoma; Inflammatory Myofibroblastic Tumor; Malignant Peripheral Nerve Sheath Tumor; Medulloblastoma; Pleuropulmonary Blastoma; Rhabdoid Tumor; Rhabdomyosarcoma; Synovial Sarcoma; Wilms Tumor |
Myoglobin |
iron and oxygen-building protein found in muscle tissue |
MG-1 |
Botryoid Rhabdomyosarcoma; Gingival Granular Cell Tumor of the Newborn; Inflammatory Myofibroblastic Tumor; Rhabdomyoma; Rhabdomyosarcoma |
Myosin |
motor protein responsible for actin-based motility |
|
Pseudoangiomatous Stromal Hyperplasia; Rhabdomyosarcoma |
N-myc |
protooncogene and member of the MYC family of transcription factors |
|
Neuroblastoma and Ganglioneuroblastoma |
Nerve growth factor |
|
NGF |
Neuroblastoma and Ganglioneuroblastoma |
Nestin |
neural stem cell marker |
10C2 |
Ependymoblastoma |
NeuN |
neuronal nuclear antigen |
A60 |
Ganglion Cell Tumors |
Neurofilament protein |
neurofilament H/M phosphorylated protein |
TPNFP-1A3, SMI31, SMI33, NFP, SMI32, TA-51, 2F11 |
Atypical Teratoid/Rhabdoid Tumor; Diffuse Astrocytoma (Low Grade); Neurofibroma |
NFP |
neurofilament H/M phosphorylated protein |
TPNFP-1A3, SMI31, SMI33, NFP, SMI32, TA-51, 2F11 |
Atypical Teratoid/Rhabdoid Tumor; Diffuse Astrocytoma (Low Grade); Medulloblastoma; Neurofibroma |
NGFR |
nerve growth factor receptor |
|
Teratomas |
NOTCH1 |
translocation-associated notch protein |
|
T Lymphoblastic Leukemia/Lymphoma |
NSE |
neuron specific enolase |
BSS/H14 |
Adrenal Cortical Carcinoma; Burkitt Lymphoma; Ewing Sarcoma; Gingival Granular Cell Tumor of the Newborn; Infantile Fibrosarcoma; Medulloblastoma; Melanotic Neuroectodermal Tumor of Infancy; Neuroblastoma and Ganglioneuroblastoma; Neuroendocrine Tumors; Neurothekeoma; Pineal Parenchymal Tumors; Rhabdoid Tumor; Subependymal Giant Cell Tumor; Teratomas |
Nuclear p53 |
p53 tumor suppressor gene protein |
D07, 21N, BP53-12-1, AB6, CM1, PAB1801, DO1, BP53-11, PAP240, RSP53, MU195, P53 |
Choroid Plexus Tumors |
O13 |
CD 99 (cell surface glycoprotein for migration, T-cell adhesion, MIC2) |
CD99-MEMB, CD 99, MIC2, 12E7, HBA71, P30/32MIC2, M3601 |
Ewing Sarcoma |
OCT2 |
octamer binding transcription factor 2 |
SC233 |
Classical Hodgkin Lymphoma; Primary Mediastinal (Thymic) Large B-Cell Lymphoma |
OCT4 |
octamer-binding transcription factor-3 |
OCT3, POU5F1 (OCT3/4), C-10 |
Gonadoblastoma |
p16 |
cyclin dependent kinase 4 inhibitor A |
Cyclin dependent kinase inhibitor p16 antibody, INK4, INK4a, MLM, MTS1, multiple tumor suppressor 1 antibody, p12, p14, p16 γ, p16 INK4, p16 INK4a, INK4 p19, TP16, P16_INK4A, E6H4, sc1661, JC8, ZJ11, G175-405, F-12, DCS-50, 6H12, 16P07, 16P04 |
Glioblastoma; Malignant Melanoma |
p53 |
p53 tumor suppressor gene protein |
DO7, 21N, BP53-12-1, AB6, CM1, PAB1801, DO1, BP53-11, PAB240, RSP53, MU195, PAB1801, nuclear p53, P53 |
Adrenal Cortical Carcinoma; Choroid Plexus Tumors; Clear Cell Sarcoma; Diffuse Astrocytoma (Low Grade); Glioblastoma; Inflammatory Myofibroblastic Tumor; Medulloblastoma; Neurofibroma; Oligodendroglioma; Pediatric Follicular Lymphoma; Pleomorphic Adenoma; Sialoblastoma; Wilms Tumor |
p63 |
tumor protein p63 |
P63-P53 HOMOLOGOUS NULCEAR PROTEIN;DELTA-NP63, 4A4, P63, H-137, 7JUL |
Fibroadenoma; Mucoepidermoid Carcinoma; Pleomorphic Adenoma; Secretory Carcinoma; Sialoblastoma; Thymoma; Trichoepithelioma |
p73 |
tumor protein p73 |
AB7824 |
Burkitt Lymphoma |
PAP |
Prostatic acid phosphatase |
PASE/4LJ, PAP-P |
Medullary Thyroid Carcinoma |
pax-2 |
paired box gene 2 |
Z-RX2, PAX-2 |
Wilms Tumor |
pax-5 |
paired box gene 5 |
PAX5 (BSAP) |
Burkitt Lymphoma;; Classical Hodgkin Lymphoma Diffuse Large B-Cell Lymphoma; Nodular Lymphocyte Predominant Hodgkin Lymphoma; Primary Mediastinal (Thymic) Large B-Cell Lymphoma |
PD-1 |
programmed cell death protein 1 |
EH12, NAT105, programmed death 1 |
Diffuse Large B-Cell Lymphoma |
Perforin |
|
P1-8, PE-41-PU, 5B10 |
Anaplastic Large Cell Lymphoma, ALK +; Autoimmune Lymphoproliferative Syndrome; Hemophagocytic Syndrome |
PG-M1 |
cytoplasmic granule protein of monocytes, macrophages |
CD-68, KP-1, LN5 |
Myeloid Sarcoma |
PGP9.5 |
protein gene product 9.5 |
31A3, 13C4 |
Neurothekeoma; Pineal Parenchymal Tumors |
PLAP |
placental alkaline phosphatase |
228M, 8A9, 88B |
Choroid Plexus Tumors; Dysgerminoma |
Podoplanin |
transmembrane mucoprotein (38 kd) recognized by the D2-40 monoclonal antibody |
D2-40, M2A |
Fibrous Histiocytoma; Giant Cell Fibroblastoma/Dermatofibrosarcoma Protuberans; Kaposiform Hemangioendothelioma |
POU5F1 |
octamer-binding transcription factor-3 |
OCT3, OCT4, C-10 |
Gonadoblastoma |
PR |
progesterone receptor protein |
PRP, 10A9, PGR-1A6, KD68, PGR-ICA, PRP-P, PRI, 1A6, 1AR, HPRA3, PGR-636, 636, PR88, NCL-PGR |
Gingival Granular Cell Tumor of the Newborn; Secretory Carcinoma |
Prealbumin |
carrier protein of thyroxin and retinol; rich in a beta sheet structure |
Transthyretin |
Choroid Plexus Tumors |
Prolactin |
|
PRL |
Chordoma; Juvenile (Virginal) Hypertrophy |
Protein gene product 9.5 |
|
31A3, 13C4 |
Neuroblastoma and Ganglioneuroblastoma |
Protein Kinase C Theta |
|
PKC-θ, CLONE 27, PKC-THETA |
Gastrointestinal Stromal Tumor |
PROX1 |
critical regulator of lymphangiogenesis |
|
Lymphatic Malformation |
PRP |
progesterone receptor protein |
PR, 10A9, PGR-1A6, KD68, PGR-ICA, PRP-P, PRI, 1A6, 1AR, HPRA3, PGR-636, 636, PR88, NCL-PGR |
Craniopharyngioma |
PTEN |
phosphatase and tensin homolog |
PN37 |
Anaplastic Astrocytoma; Fibrolipomatous Hamartoma of Nerve; Follicular Adenoma; Follicular Carcinoma; Glioblastoma; Papillary Thyroid Carcinoma |
PTH |
parathyroid hormone |
|
Medullary Thyroid Carcinoma |
PU.1 |
transcription factor PU.1 |
PTX1 |
Primary Mediastinal (Thymic) Large B-Cell Lymphoma |
Renin |
participates in renin-angiotensisn system |
Angiotensinase |
Adrenal Cortical Adenoma; Mesoblastic Nephroma |
ret |
Multiple endocrine neoplasia and medullary thyroid carcinoma 1 |
3F8 |
Medullary Thyroid Carcinoma; Papillary Thyroid Carcinoma |
Retinal S antigen |
localized to the photoreceptor cell layer of the retina |
|
Medulloblastoma Primitive Neuroectodermal Tumor |
Rhodopsin |
photoreceptor that mediates dim-light vision |
|
Medulloblastoma; Pineal Parenchymal Tumors; Primitive Neuroectodermal Tumor |
S100 |
Low molecular weight protein normally present in cells derived from neural crest (Schwann cells, melanocytes, and glial cells), chondrocytes, adipocytes, myoepithelial cells, macrophages, Langerhans cells, dendritic cells, and keratinocytes |
S-100, A6, 15E2E2, Z311, 4C4.9, S100 protein |
Adrenal Cortical Adenoma; Adrenal Cortical Carcinoma; Atypical Teratoid/Rhabdoid Tumor; Blue Nevus; Burkitt Lymphoma; Calcifying Fibrous Tumor; Chondroblastoma; Chondrosarcoma; Chordoma; Choroid Plexus Tumors; Clear Cell Sarcoma; Desmoplastic Small Round Cell Tumor; Diffuse Astrocytoma (Low Grade); Ependymoma; Ewing Sarcoma; Fibrous Umbilical Polyp; Gastrointestinal Stromal Tumor; Giant Cell Fibroblastoma/Dermatofibrosarcoma Protuberans; Gingival Granular Cell Tumor of the Newborn; Glioblastoma; Infantile Fibrosarcoma; Inflammatory Myofibroblastic Tumor; Inflammatory Polyps; Juvenile Xanthogranuloma; Langerhans Cell Histiocytosis; Malignant Melanoma; Malignant Peripheral Nerve Sheath Tumor; Medullary Thyroid Carcinoma; Melanocytic Nevus; Meningioangiomatosis; Mucoepidermoid Carcinoma; Myofibroma and Myofibromatosis; Neuroblastoma and Ganglioneuroblastoma; Neuroendocrine Tumors; Neurofibroma; Neurothekeoma; Oligodendroglioma; Pleomorphic Adenoma; Pleomorphic Xanthoastrocytoma; Schwannoma; Secretory Carcinoma; Sialoblastoma; Subependymal Giant Cell Tumor; Synovial Sarcoma |
S100P |
S100 placental |
S100-pla |
Teratomas |
SMAD4 |
Similar to Mothers Against Decapentaplegic (MAD); mothers against DPP homolog 4 |
MADR1 JV4-1, DPC4_SMAD4, B-8 |
Cronkite-Canada Syndrome; Juvenile Polyps; Pancreatoblastoma |
SMHC |
myosin heavy chain smooth muscle |
ID8, SM_MYOSIN_H, HSM-V, SMMS-1 |
Pleomorphic Adenoma; Pseudoangiomatous Stromal Hyperplasia |
Smooth muscle myosin |
myosin heavy chain smooth muscle |
ID8, SM_MYOSIN_H, HSM-V, SMMS-1 |
Pseudoangiomatous Stromal Hyperplasia |
SNF5 |
member of SWI/SNF chromatin remodeling complex |
BAF47/SNF5, INI1 |
Atypical Teratoid/Rhabdoid Tumor; Rhabdoid Tumor |
Sodium iodine symporter |
|
Na-I symporter |
Papillary Thyroid Carcinoma |
Somatostatin |
|
|
Craniopharyngioma |
SOX9 |
SRY (sex-determining region Y)-box 9 protein |
CMD1, CMPD1 |
Chondromyxoid Fibroma |
SOX10 |
SRY (sex-determining region Y)-box 10 protein |
|
Malignant Melanoma |
Stem cell factor |
|
SCF |
Mastocytosis |
Survivin |
inhibitor of apoptosis |
AB469, SURVIVIN, FL-142, D8, 8E12 |
Medulloblastoma |
SV40 |
simian virus 40 |
|
Choroid Plexus Tumors; Ependymoma; Medulloblastoma |
Synaptophysin |
major synaptic vesicle protein p38 antibody |
SVP38, SY38, SNP-88, SYP, SYPH, Sypl, Syn p38 |
Adrenal Cortical Adenoma; Adrenal Cortical Carcinoma; Atypical Teratoid/Rhabdoid Tumor; Desmoplastic Small Round Cell Tumor; Diffuse Large B-Cell Lymphoma; Ependymoma; Ewing Sarcoma; Follicular Adenoma; Follicular Carcinoma; Ganglion Cell Tumors; Islet Cell Adenoma; Medullary Thyroid Carcinoma; Medulloblastoma; Melanotic Neuroectodermal Tumor of Infancy; Neuroblastoma and Ganglioneuroblastoma; Neuroendocrine Tumors; Pancreatoblastoma; Pineal Parenchymal Tumors; Pleomorphic Xanthoastrocytoma; Primitive Neuroectodermal Tumor; Sertoli-Leydig Cell Tumors; T Lymphoblastic Leukemia/ Lymphoma; Teratomas; Thymoma |
SYT |
SYT homolog 1 |
|
Calcifying Aponeuronic Fibroma; Ewing Sarcoma |
TAU |
microtubule-associated protein of axons AT8 |
|
Ganglion Cell Tumors; Pineal Parenchymal Tumors |
TCR |
T-cell receptor antigen |
T_Cell_AG_R, Beta-F1, 8A3, BF1 |
Autoimmune Lymphoproliferative Syndrome; Overview of Lymphoproliferative Disorders Associated with Primary Immune Deficiency; Primary Mediastinal (Thymic) Large B-Cell Lymphoma; T Lymphoblastic Leukemia/ Lymphoma |
TdT |
terminal deoxynucleotidyl transferase |
SEN28 |
Autoimmune Lymphoproliferative Syndrome; B Lymphoblastic Leukemia/ Lymphoma; Burkitt Lymphoma; Desmoplastic Small Round Cell Tumor; Diffuse Large B-Cell Lymphoma; Primary Mediastinal (Thymic) Large B-Cell Lymphoma; T Lymphoblastic Leukemia/ Lymphoma; Thymoma |
Terminal deoxyneucleotidyl transferase |
|
SEN28, TdT |
B Lymphoblastic Leukemia/Lymphoma; Myeloid Sarcoma |
TFE3 |
transcription factor E3 |
|
MiTF/TFE Family Translocation-associated Carcinoma |
TFEB |
transcription factor EB |
|
MiTF/TFE Family Translocation-associated Carcinoma |
Thyroglobulin |
dimetric protein specific to thyroid gland |
DAK-TG6 |
Follicular Adenoma; Follicular Carcinoma; Medullary Thyroid Carcinoma |
TIA |
T-cell intracellular antigen 1 |
NS/1-AG4, 2G9, TIA-1 |
Anaplastic Large Cell Lymphoma, ALK+ |
TIA-1 |
T-cell intracellular antigen 1 |
NS/1-AG4, 2G9, TIA |
Anaplastic Large Cell Lymphoma, ALK+ |
TLE1 |
transducer like enhancer 1 |
|
Malignant Peripheral Nerve Sheath Tumor; Synovial Sarcoma |
TNF-α |
cytokine involved in systemic inflammation, stimulates the acute phase reaction |
Gamma catenin, γ-catenin, G-catenin, alpha alpha, TNF, cachexin, cachectin |
Classical Hodgkin Lymphoma |
TRAF1 |
tumor necrosis factor receptor 1 |
|
Primary Mediastinal (Thymic) Large B-Cell Lymphoma |
Transcription factor EB |
|
TFEB |
MiTF/TFE Family Translocation-associated Carcinoma |
Tryptase |
serine proteinase contained in mast cells |
|
Mastocytosis |
TSH |
thyroid stimulating hormone |
beta-TSH |
Follicular Carcinoma |
TTF-1 |
transcription termination factor |
8G7G3/1, SPT-24, SC-13040 |
Follicular Adenoma; Follicular Carcinoma; Medullary Thyroid Carcinoma; Papillary Thyroid Carcinoma; Teratomas |
Tuberin |
|
Tuberous sclerosis protein 2, TSC2 |
Subependymal Giant Cell Tumor |
TUJ1 |
beta tubulin |
B-tubulin, β-tubulin |
Subependymal Giant Cell Tumor |
Tyrosinase |
catalyzes production of melanin |
NCL-TYROS, T311 |
Malignant Melanoma |
Ubiquitin |
Small regulatory protein that binds proteins and labels them for destruction |
|
Ganglion Cell Tumors; Juvenile Myelomonocytic Leukemia; Pilocytic Astrocytoma; Rhabdomyoma |
Vascular endothelial growth factor |
|
VEGF, JH121, 26503.11, VPF, VPF/VEGF, VEGFA, VEGF-C, RP 077, VEGFR-1, RP 076, VEGFR-2, 9D9, VEGFR-3, FLT-4 |
Lymphatic Malformation |
VEGF |
vascular endothelial growth factor |
JH121, 26503.11, VPF, VPF/VEGF, VEGFA, VEGF-C, RP 077, VEGFR-1, RP 076, VEGFR-2, 9D9, VEGFR-3, FLT-4 |
Adrenal Cortical Carcinoma; Hemangioma of Infancy; Pilocytic Astrocytoma |
Vimentin |
major subunit protein of the intermediate filaments of mesenchymal cells |
43BE8, 3B4, V10, V9, VIM-3B4, VIM |
Adrenal Cortical Carcinoma; Anaplastic Astrocytoma; Atypical Teratoid/Rhabdoid Tumor; Chondroblastoma; Chondrosarcoma; Chordoma; Choroid Plexus Tumors; Clear Cell Sarcoma; Desmoid Fibromatosis; Desmoplastic Small Round Cell Tumor; Ependymoblastoma; Ependymoma; Ewing Sarcoma; Fibroma; Fibrous Hamartoma of Infancy; Gastrointestinal Stromal Tumor; Gingival Granular Cell Tumor of the Newborn; Glioblastoma; Glomus Tumor; Inclusion Body Fibromatosis; Infantile Fibromatosis; Infantile Fibrosarcoma; Inflammatory Myofibroblastic Tumor; Medulloblastoma; Mesoblastic Nephroma; MiTF/TFE Family Translocation-associated Carcinoma; Myofibroma and Myofibromatosis; Neurofibroma; Oligodendroglioma; Omental Mesenteric Hamartoma; Pancreatoblastoma; Pleomorphic Adenoma; Pleuropulmonary Blastoma; Rhabdoid Tumor; Synovial Sarcoma; Wilms Tumor |
VIP |
vasoactive intestinal peptide |
|
Islet Cell Adenoma |
WT1 |
Wilms tumor gene 1 |
6F-H2, C-19 |
Acute Myeloid Leukemia; Desmoplastic Small Round Cell Tumor; Myeloid Sarcoma; Rhabdomyosarcoma; Wilms Tumor |
