Antibody Name/Symbol |
Antibody Description |
Clones/Alternative Names |
Chapters |
β-catenin |
beta catenin; involved in regulation of cell adhesion and in signal transduction through Wnt pathway |
B-catenin, CLONE 14, E-5, RB-9035Po, 17C2, 5H10 |
Nodular Fasciitis |
Actin-sm |
actin, smooth muscle |
SMA, ASM-1, CGA7, 1A4, HUC1-1 |
Nodular Fasciitis |
AE1/AE3 |
mixture of 2 anticytokeratin clones that detect a variety of both high and low molecular weight cytokeratins |
|
Rheumatoid Nodule |
Bartonella henselae |
|
anti-Bartonella henselae (cat scratch disease) antibody |
Cat Scratch Disease/Bacillary Angiomatosis |
Basic fibroblast growth factor |
|
FGF2, BFGF, BASIC FGF |
Stasis Dermatitis |
BAX |
Bcl-2-associated X protein |
PU-347-P, B-9, BAX-P, P19, BAX-M |
Darier Disease |
Bcl-2 |
B-cell lymphoma 2; suppresses apoptosis in a variety of cell systems |
ONCL2, BCL2/100/D5, 124, 124.3 |
Darier Disease |
Bcl-x |
member of the BCL-2 family of proteins that functions in the regulation of apoptosis |
BCL-X1; BCL-XL; 2H12 |
Darier Disease |
BP180 |
transmembrane protein of the cutaneous basement membrane that plays an important role in epidermal-dermal adhesion |
bullous pemphigoid antigen 180, Collagen XVII |
Cicatricial Pemphigoid; Linear IgA Disease; Pemphigoid Gestationis |
BPAg-1 |
180 kDa type II transmembrane protein associated with hemidesmosomes in basal keratinocytes |
bullous pemphigoid antigen 1, BPAG1 |
Epidermolysis Bullosa Acquisita |
Caldesmon |
actin-interacting and calmodulin-binding protein found in smooth muscle and other cell types |
|
Nodular Fasciitis |
Calponin |
thin filament-associated protein that is implicated in regulation and modulation of smooth muscle contraction |
N3, 26A11, CALP, CNN1, SMCC, Sm Calp |
Nodular Fasciitis |
CCL17 |
thymus and activation regulated chemokine |
TARC |
Atopic Dermatitis |
CD1a |
T-cell surface glycoprotein |
JPM30, CD1A, O10, NA1/34 |
Lichen Nitidus; Transient Neonatal Pustular Melanosis |
CD3 |
T-cell receptor |
F7238, A0452, CD3-P, CD3-M, SP7, PS1 |
Lyme Disease and Its Manifestations |
CD4 |
T-cell surface glycoprotein, L3T4 |
IF6, 1290, 4B12, 1F6, CD04 |
Aspergillosis; Atypical Mycobacterial Infections; Cryptococcosis; Morbilliform Drug Reactions; Psoriasis; Rhinoscleroma; Sarcoidosis; Sporotrichosis |
CD8 |
T-cell coreceptor antigen, Leu 2, T-cytotoxic cells |
M7103, C8/144, C8/144B |
Morbilliform Drug Reactions; Sarcoidosis |
CD20 |
glycosylated phosphoprotein expressed on the surface of B cells |
BER-H2, KI-1, TNFRSF8 |
Lyme Disease and Its Manifestations |
CD25 |
If-2 receptor alpha |
2A3, 4C9 |
Fixed Drug Eruption |
CD31 |
platelet endothelial cell adhesion molecule |
JC/70, JC/70A, PECAM-1 |
Nodular Fasciitis |
CD34 |
cell surface glycoprotein that functions in cell to cell adhesion in stem and stromal cells |
MY10, IOM34, QBEND10, 8G12, 1309, HPCA-1, NU-4A1, TUK4, clone 581, BI-3c5 |
Nodular Fasciitis |
CD54 |
ICAM-1 (intracellular adhesion molecule 1) |
23G12, CD54-P, ICAM |
Morbilliform Drug Reactions |
CD56 |
NCAM (neutral cellular adhesion molecule) |
MAB735, ERIC-1, 25-KD11, 123C3, 24-MB2, BC56C04, 1B6, 14-MAB735, NCC-LU-243, MOC-1, NCAM |
Granulomatosis with Polyangiitis |
CD68 |
cytoplasmic granule protein of monocytes, macrophages |
PG-M1, KP-1, LN5 |
Nodular Fasciitis |
CK-PAN |
cytokeratin-pan (AE1/AE3/LP34); cocktail of high and low molecular weight cytokeratins |
keratin pan, MAK-6, K576, LU-5, KL-1, KC-8, MNF 116, pankeratin, pancytokeratin |
Nodular Fasciitis |
CMV |
Cytomegalovirus |
|
Cytomegalovirus; Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) |
Collagen II |
major component of articular and hyaline cartilage |
2B1.5 |
Lipoid Proteinosis |
Collagen IV |
major constituent of the basement membranes along with laminins, proteoglycans, and enactins |
CIV22, COL4A [1-5], collagen α-1(IV) chain |
Lipoid Proteinosis; Perforating Dermatoses; Porphyria Cutanea Tarda |
Desmin |
class III intermediate filaments found in muscle cells |
M760, DE-R-11, D33, DE5, DE-U-10, ZC18 |
Nodular Fasciitis |
Desmoplakin |
desmosome-associated protein that functions in intercellular junctions |
|
Darier Disease; Pemphigus and Variants |
EAB903 |
cytokeratin, high molecular weight (34bE12, CK 1, 5, 10, 14) |
34b312, MA-903, CK903 |
Amyloidosis |
EBER |
Epstein-Barr virus encoded RNA |
|
Epstein-Barr Virus Infections |
EGFR |
v-erb b1 erythroblastic leukemia viral gene, epidermal growth factor receptor |
2-18C9, EGFR1, EGFR PHRMDX, NCL-R1, H11, C-ERBB-1, E30, EGFR.113, 31G73C6, 2-18C9 |
Folliculitis |
EKH4 |
monoclonal antikeratin antibody; antigen specificity is toward keratin (50 KD) |
|
Amyloidosis |
EMA |
epithelial membrane antigen |
EMA, GP1.4, 214D4, MC5, E29, MUC1, LICRLON- M8, BC3, DF3, VU3D1, MUSEII, RD-1, MA695, MA552, PS2P446, 115D8, MUC1, MAM6, CA15.3, MUC01 |
Rheumatoid Nodule |
Epidermal growth factor |
|
EGF, KME-10 |
Folliculitis |
Epidermal growth factor receptor |
v-erb b1 erythroblastic leukemia viral gene, epidermal growth factor receptor |
EGFR, 2-18C9, EGFR1, EGFR PHRMDX, NCL-R1, H11, C-ERBB-1, E30, EGFR.113, 31G73C6, 2-18C9 |
Folliculitis |
Factor XIIIa |
fibrin stabilizing factor |
FXIIIA |
Multicentric Reticulohistiocytosis |
FAS |
fatty acid synthase |
CD95/fas |
Erythema Multiforme |
Filaggrin |
filament-associated protein that binds to keratin in epithelial cells |
FLG |
Atopic Dermatitis; Granular Parakeratosis; Ichthyosis |
GM-CSF |
granulocyte macrophage colony stimulating factor |
3209.1 |
Atopic Dermatitis |
Granulocyte colony stimulating factor |
granulocyte macrophage colony stimulating factor |
3209.1, GM-CSF |
Neutrophilic Eccrine Hidradenitis; Sweet Syndrome |
HSV1 |
herpes simplex virus 1 |
|
Herpesvirus |
IgA |
immunoglobulin A |
IGA |
Atopic Dermatitis; Dermatitis Herpetiformis; Epidermolysis Bullosa Acquisita; Leukocytic Vasculitis and Variants; Lichen Nitidus; Lichen Planus; Linear IgA Bullous Dermatosis; Bullous Pemphigoid; Pemphigus and Variants; Perforating Dermatoses; Porphyria Cutanea Tarda; Relapsing Polychondritis; Subcorneal Pustular Dermatosis |
IgG |
immunoglobulin G |
IGG |
Annular Erythemas; Cicatricial Pemphigoid; Dermatitis Herpetiformis; Epidermolysis Bullosa Acquisita; Hailey-Hailey Disease; Impetigo; Lichen Myxedematosus; Lichen Planus; Linear IgA Bullous Dermatosis; Lupus Erythematosus and Variants; Bullous Pemphigoid; Pemphigoid Gestationis; Pemphigus and Variants; Polymorphous Light Eruption; Porphyria Cutanea Tarda; Staphylococcal Scalded Skin Syndrome; Subcorneal Pustular Dermatosis |
IgM |
immunoglobulin M |
IGM |
Amyloidosis; Annular Erythemas; Dermatitis Herpetiformis; Epidermolysis Bullosa Acquisita; Lichen Nitidus; Lichen Planus; Lichenoid Keratosis; Linear IgA Bullous Dermatosis; Polymorphous Light Eruption; Pruritic Urticarial Papules and Plaques of Pregnancy; Reticular Erythematous Mucinosis; Urticaria and Variants |
IL-1 |
involved in the inflammatory response, being identified as endogenous pyrogens |
|
Leukocytic Vasculitis and Variants |
IL-13 |
interleukin 13 |
|
Psoriasis |
IL-15 |
interleukin 15 |
|
Fixed Drug Eruption |
Immunoglobulin A |
|
IGA, IgA |
Porphyria Cutanea Tarda |
Intermediate filament |
neurofilament triplet protein |
|
Amyloidosis |
Kappa |
kappa light chain |
KAPPA, κ light chain |
Amyloidosis; Lyme Disease and Its Manifestations |
Lambda |
lambda light chain |
λ light chain, LAMBDA |
Amyloidosis; Lyme Disease and Its Manifestations |
Laminin |
major protein in basal lamina |
LAMININ-4C7, 4C12.8, LAM-89 |
Cicatricial Pemphigoid; Epidermolysis Bullosa (Inherited); Lipoid Proteinosis |
Laminin 5 |
component of epithelial cell basement membranes |
Antiepiligrin |
Cicatricial Pemphigoid |
MAC387 |
macrophage antibody |
|
Dermatomyositis |
Melan-A |
melanoma antigen recognized by T cells 1 (MART-1); protein found on melanocytes; melanocyte differentiation antigen |
M2-7C10, CK-MM |
Lichenoid Keratosis |
met |
met proto-oncogene |
|
Lupus Erythematosus and Variants |
Perforin |
|
P1-8, PE-41-PU, 5B10 |
Graft vs. Host Disease; Morbilliform Drug Reactions |
S100 |
low molecular weight protein normally present in cells derived from neural crest (Schwann cells, melanocytes, and glial cells), chondrocytes, adipocytes, myoepithelial cells, macrophages, Langerhans cells, dendritic cells, and keratinocytes |
S-100, A6, 15E2E2, Z311, 4C4.9 |
Lichen Nitidus; Nodular Fasciitis; Prurigo Nodularis; Transient Neonatal Pustular Melanosis; Juvenile Xanthogranuloma |
Somatostatin |
|
|
Necrolytic Migratory Erythema |
Tissue plasminogen activator |
serine protease that catalyzes the conversion of plasminogen to plasmin |
TPA, tPA, PLAT |
Livedoid Vasculopathy |
TNF-α |
cytokine involved in systemic inflammation, stimulates the acute phase reaction |
Gamma catenin, y-catenin, G-catenin, alpha alpha, TNF, cachexin, cachectin |
Cicatricial Pemphigoid; Fixed Drug Eruption; Graft vs. Host Disease; Hidradenitis Suppurativa; Morbilliform Drug Reactions; Necrobiosis Lipoidica; Pityriasis Rubra Pilaris; Psoriasis |
Transthyretin |
carrier protein of thyroxin and retinol; rich in a beta sheet structure |
Prealbumin |
Amyloidosis |
V-Alpha |
T-cell antigen receptor alpha chain |
TCR-α |
Relapsing Polychondritis |
V-Beta 11 |
Antibody directed toward the beta chain of the TCR-αβ heterodimer |
TCR-β |
Relapsing Polychondritis |
Vimentin |
major subunit protein of intermediate filaments of mesenchymal cells |
43BE8, 3B4, V10, V9, VIM-B34, VIM |
Granuloma Faciale; Nodular Fasciitis |
