Schnitzler Syndrome

Nov 8, 2018 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Schnitzler Syndrome

Schnitzler Syndrome Viktoryia Kazlouskaya Jacqueline M. Junkins-Hopkins INTRODUCTION Schnitzler syndrome (SchS) is a rare and often underreported chronic multisystem disorder, diagnosed on the basis of the presence of two major…

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Pyoderma Gangrenosum

Nov 8, 2018 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Pyoderma Gangrenosum

Pyoderma Gangrenosum Campbell L. Stewart Roberto Novoa DEFINITION Pyoderma gangrenosum (PG) is a rare, ulcerative cutaneous disease of unknown etiology. Its diagnosis critically relies upon the exclusion of other causes…

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Granuloma Annulare–Like Reactions

Nov 8, 2018 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Granuloma Annulare–Like Reactions

Granuloma Annulare–Like Reactions Karolyn A. Wanat Misha Rosenbach INTRODUCTION Cutaneous granulomatous inflammation has been reported in association with underlying lymphoproliferative disorders in primarily two patterns: granulomas within or surrounding the…

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Cryoglobulinemia

Nov 8, 2018 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Cryoglobulinemia

Cryoglobulinemia Alejandro A. Gru DEFINITION Cryoglobulins are abnormal serum immunoglobulins that reversibly precipitate at low temperature. Two forms of cryoglobulinemias are distinguished based on the composition of the cryoglobulins and…

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Paraneoplastic Pemphigus

Nov 8, 2018 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Paraneoplastic Pemphigus

Paraneoplastic Pemphigus Milda Chmieliauskaite Faizan Alawi INTRODUCTION Paraneoplastic pemphigus (PNP) is an autoimmune vesiculobullous disorder.1 PNP was first described in 1990 as a distinct clinical entity different from pemphigus vulgaris…

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Vasculitis

Nov 8, 2018 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Vasculitis

Vasculitis Alejandro A. Gru INTRODUCTION Vasculitis refers to a heterogeneous group of disorders characterized by vessel inflammation.1 The clinical manifestations range from locoregional ischemic and purpuric injuries to systemic disease….

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Sweet and Histiocytoid Sweet Syndrome

Nov 8, 2018 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Sweet and Histiocytoid Sweet Syndrome

Sweet and Histiocytoid Sweet Syndrome Viktoryia Kazlouskaya Jacqueline M. Junkins-Hopkins DEFINITION Sweet syndrome (SS), also known as acute neutrophilic dermatosis, is a predominantly neutrophilic disorder, frequently associated with systemic involvement….

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