Gallbladder Carcinoma Cancer Protocol



Gallbladder Carcinoma Cancer Protocol


Laura Webb Lamps, MD










Gallbladder: Resection/Cholecystectomy























































































































































































































































































































Surgical Pathology Cancer Case Summary (Checklist)


Specimen (select all that apply)



___Gallbladder



___Liver



___Extrahepatic bile duct



___Other (specify):____________________



___Not specified


Procedure



___Simple cholecystectomy (laparoscopic or open)



___Radical cholecystectomy (with liver resection and lymphadenectomy)



___Other (specify):____________________



___Not specified


Tumor Site (select all that apply)



___Fundus



___Body



___Neck



___Cystic duct



___Free peritoneal side of gallbladder



___Hepatic side of gallbladder



___Cannot be determined



___Other (specify):____________________



___Not specified


Tumor Size



Greatest dimension: __________ cm



*Additional dimensions: __________ x __________ cm



___Cannot be determined


Histologic Type



___Adenocarcinoma, not otherwise specified



___Papillary adenocarcinoma



___Adenocarcinoma, intestinal type



___Mucinous carcinoma



___Signet ring cell carcinoma



___Clear cell carcinoma



___Squamous cell carcinoma



___Adenosquamous carcinoma



___Small cell carcinoma



___Undifferentiated carcinoma



___Carcinoma, not otherwise specified



___Carcinosarcoma



___Other (specify):__________


Microscopic Tumor Extension



___Tumor invades lamina propria



___Tumor invades muscle layer



___Tumor invades perimuscular connective tissue; no extension beyond serosa or into liver



___Tumor perforates serosa (visceral peritoneum)



___Tumor directly invades liver



___Tumor directly invades extrahepatic bile ducts



___Tumor directly invades other adjacent organ or structure, such as stomach, duodenum, colon, pancreas, or omentum (specify):____________________


Margins (select all that apply)



___Cannot be assessed



___Margins uninvolved by invasive carcinoma





Distance of invasive carcinoma from closest margin: _____ mm





Specify margin:________________



___Margins involved by invasive carcinoma





Specify margin(s):________________



___Cystic duct margin uninvolved by intramucosal carcinoma



___Cystic duct margin involved by intramucosal carcinoma


* Lymph-Vascular Invasion



*___Not identified



*___Present


*Perineural Invasion



*___Not identified



*___Present


Pathologic Staging (pTNM)



TNM descriptors (required only if applicable) (select all that apply)




___m (multiple primary tumors)




___r (recurrent)




___y (post-treatment)



Primary tumor (pT)




___pTX: Cannot be assessed




___pT0: No evidence of primary tumor




___pTis: Carcinoma in situ





pT1: Tumor invades lamina propria or muscular layer





___pT1a: Tumor invades lamina propria





___pT1b: Tumor invades muscle layer




___pT2: Tumor invades perimuscular connective tissue; no extension beyond serosa or into liver




___pT3: Tumor perforates serosa (visceral peritoneum) &/or directly invades liver &/or 1 other adjacent organ or structure, such as the stomach, duodenum, colon, pancreas, omentum, or extrahepatic bile ducts




___PT4: Tumor invades main portal vein or hepatic artery or invades 2 or more extrahepatic organs or structures



Regional lymph nodes (pN)




___pNX: Cannot be assessed




___pN0: No regional lymph node metastasis




___pN1: Metastases to nodes along cystic duct, common bile duct, hepatic artery, &/or portal vein






Specify: Number examined:_____







Number involved:_____




___pN2: Metastases to periaortic, cervical, superior mesentery artery, &/or celiac artery lymph nodes






Specify: Number examined:_____







Number involved:_____



Distant metastasis (pM)




___Not applicable




___pM1: Distant metastasis






*Specify site(s), if known:____________________


* Data elements with asterisks are not required. However, these elements may be clinically important but are not yet validated or regularly used in patient management. Adapted with permission from College of American Pathologists, “Protocol for the Examination of Specimens from Patients with Carcinoma of the Gallbladder.” Web posting date October 2009, www.cap.org. Protocol applies to all invasive carcinomas of the gallbladder and cystic duct, including those showing focal endocrine differentiation. Well-differentiated neuroendocrine neoplasms (carcinoid tumors) are not included.

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Jul 7, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Gallbladder Carcinoma Cancer Protocol

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